Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …

Synthetic organic electrosynthesis has grown in the past few decades by achieving many
valuable transformations for synthetic chemists. Although electrocatalysis has been popular …

During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

This Review summarizes the advancements in Pd-catalyzed C (sp3)–H activation via
various redox manifolds, including Pd (0)/Pd (II), Pd (II)/Pd (IV), and Pd (II)/Pd (0). While few …

Transition metal-catalyzed direct functionalization of C–H bonds is one of the key emerging
strategies that is currently attracting tremendous attention with the aim to provide alternative …

Conspectus In recent years, carbon–hydrogen bond functionalization has evolved from an
organometallic curiosity to a tool used in mainstream applications in the synthesis of …

The late‐stage modification of structurally complex peptides bears great potential for drug
discovery, crop protection, and the pharmaceutical industry, among others. Whereas …

The construction of carbon–carbon bonds is a central tenet of modern synthetic chemistry.
Metal-catalyzed C–H functionalization can serve as a particularly powerful tool for achieving …

C H bonds are ubiquitous in organic compounds. It would, therefore, appear that direct
functionalization of substrates by activation of C H bonds would eliminate the multiple …

Conspectus α-Amino acids (αAA) are one of the most useful chiral building blocks for
synthesis. There are numerous general strategies that have commonly been used for αAA …