Leishmaniasis affects over 150 million people all over the world, especially in subtropical
regions. Currently used antileishmanial synthesized drugs are associated with some …

Leishmania, one of the most important neglected tropical diseases, is endemic in several
regions of the world and hence regarded as a serious threat to public health. Major …

Candidates of triazole-containing amino acid derivatives 5a− k were prepared under green
chemistry conditions via multicomponent reaction using lemon juice as an acidic catalyst. All …

Quinazolinones are a diverse group of nitrogen-containing heterocyclic compounds with
promising antimalarial and antileishmanial activities. Herein, some 3-aryl-2-styryl substituted …

The development of hybrid molecules with significant human therapeutic properties is one of
the main approaches of pharmaceutical research. One of the most important …

Background Malaria is a neglected tropical parasitic disease affecting billons of people
around the globe. Though the number of cases and deaths associated with malaria are …

With the aim to identify a potential drug candidate to treat cutaneous leishmaniasis, a series
of 1-phthalazinyl hydrazones were synthesized and tested against Leishmania braziliensis …

To identify new agents for the American Cutaneous Leishmaniasis treatment, a series of 2-
aryl-quinazolin-4 (3H)-ones were tested against L. mexicana, L. braziliensis and L …

A highly efficient and straightforward one-pot synthesis of diversely substituted 3, 4-
dihydroquinazolines and quinazolin-4 (3 H)-ones has been achieved through a domino …

Pyrazole-bearing compounds are known for their diverse pharmacological effects including
potent antileishmanial and antimalarial activities. Herein, some hydrazine-coupled …