MRI biomarkers in neuro-oncology

M Smits - Nature Reviews Neurology, 2021 - nature.com
The central role of MRI in neuro-oncology is undisputed. The technique is used, both in
clinical practice and in clinical trials, to diagnose and monitor disease activity, support …

Primary brain tumours in adults

MJ van den Bent, M Geurts, PJ French, M Smits… - The Lancet, 2023 - thelancet.com
The most frequent adult-type primary CNS tumours are diffuse gliomas, but a large variety of
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …

Radiomics for precision medicine in glioblastoma

K Aftab, FB Aamir, S Mallick, F Mubarak… - Journal of neuro …, 2022 - Springer
Introduction Being the most common primary brain tumor, glioblastoma presents as an
extremely challenging malignancy to treat with dismal outcomes despite treatment. Varying …

Multiparametric MRI: practical approach and pictorial review of a useful tool in the evaluation of brain tumours and tumour-like lesions

V Sawlani, MD Patel, N Davies, R Flintham… - Insights into …, 2020 - Springer
MRI has a vital role in the assessment of intracranial lesions. Conventional MRI has limited
specificity and multiparametric MRI using diffusion-weighted imaging, perfusion-weighted …

EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma

QJ Gai, Z Fu, J He, M Mao, XX Yao, Y Qin… - Signal transduction and …, 2022 - nature.com
Platelet-derived growth subunit A (PDGFA) plays critical roles in development of
glioblastoma (GBM) with substantial evidence from TCGA database analyses and in vivo …

Radiomics nomogram building from multiparametric MRI to predict grade in patients with glioma: a cohort study

Q Wang, Q Li, R Mi, H Ye, H Zhang… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Accurate classification of gliomas is crucial for prescribing therapy and
assessing the prognosis of patients. Purpose To develop a radiomics nomogram using …

Advanced imaging techniques for radiotherapy planning of gliomas

A Castellano, M Bailo, F Cicone, L Carideo… - Cancers, 2021 - mdpi.com
Simple Summary Conventional magnetic resonance imaging (MRI) sequences have known
limitations in target delineation for radiation treatment (RT) planning of cerebral gliomas …

Arterial spin labeling: techniques, clinical applications, and interpretation

T Iutaka, MB de Freitas, SS Omar, FA Scortegagna… - Radiographics, 2022 - pubs.rsna.org
Arterial spin labeling (ASL) is an emerging noninvasive MRI technique for assessing
cerebral perfusion. An important advantage of ASL perfusion is the lack of a requirement for …

[HTML][HTML] Advanced diagnosis of glioma by using emerging magnetic resonance sequences

RL Wei, XT Wei - Frontiers in Oncology, 2021 - frontiersin.org
Glioma, the most common primary brain tumor in adults, can be difficult to discern
radiologically from other brain lesions, which affects surgical planning and follow-up …

FAP-specific PET signaling shows a moderately positive correlation with relative CBV and no correlation with ADC in 13 IDH wildtype glioblastomas

M Röhrich, R Floca, L Loi, S Adeberg… - European journal of …, 2020 - Elsevier
Abstract Objectives Targeting Fibroblast Activation Protein (FAP) is a new approach for
glioblastoma imaging. In a recent pilot study glioblastomas showed elevated tracer uptake …