Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …

Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …

Sex based differences in immune responses, affecting both the innate and adaptive immune
responses, contribute to differences in the pathogenesis of infectious diseases in males and …

Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …

Multiple sclerosis (MS) is probably aetiologically heterogeneous. Systematic genetic
epidemiological and molecular genetic studies have provided important insights. Both …

Relapses (episodic exacerbations of neurological signs or symptoms) are a defining feature
of relapsing-remitting multiple sclerosis (MS), the most prevalent MS phenotype. While their …

Variation in major histocompatibility complex genes on chromosome 6p21. 3, specifically the
human leukocyte antigen HLA-DR2 or DRB1* 1501-DQB1* 0602 extended haplotype …

Objective Antibodies against leucine-rich glioma-inactivated 1 (LGI1-Abs) characterize a
limbic encephalitis (LE) strongly associated with HLA-DRB1* 07: 01, although some patients …

A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57
associated genetic loci have been identified. We have undertaken a meta-analysis of …

An association between multiple sclerosis (MS) and the human leukocyte antigen (HLA)
complex, a dense cluster of genes on the short arm of chromosome 6, was first noted over …