Melatonin and phytomelatonin: Chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—An overview

G Mannino, C Pernici, G Serio, C Gentile… - International Journal of …, 2021 - mdpi.com
Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of
several physiological processes in both animals and plants. In the last century, it was …

Melatonin, a full service anti-cancer agent: inhibition of initiation, progression and metastasis

RJ Reiter, SA Rosales-Corral, DX Tan… - International journal of …, 2017 - mdpi.com
There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer's disease

C Chen, C Yang, J Wang, X Huang… - Journal of Pineal …, 2021 - Wiley Online Library
While melatonin is known to have protective effects in mitochondria‐related diseases, aging,
and neurodegenerative disorders, there is poor understanding of the effects of melatonin …

[HTML][HTML] Dietary sources and bioactivities of melatonin

X Meng, Y Li, S Li, Y Zhou, RY Gan, DP Xu, HB Li - Nutrients, 2017 - mdpi.com
Insomnia is a serious worldwide health threat, affecting nearly one third of the general
population. Melatonin has been reported to improve sleep efficiency and it was found that …

Studies on oxidants and antioxidants with a brief glance at their relevance to the immune system

BA Aslani, S Ghobadi - Life sciences, 2016 - Elsevier
Free radical generation occurs continuously within cells as a consequence of common
metabolic processes. However, in high concentrations, whether from endogenous or …

Physiological effects of melatonin: role of melatonin receptors and signal transduction pathways

SR Pandi-Perumal, I Trakht, V Srinivasan… - Progress in …, 2008 - Elsevier
Melatonin, an endogenous signal of darkness, is an important component of the body's
internal time-keeping system. As such it regulates major physiological processes including …

Молекулярные и физиологические механизмы старения

ВН Анисимов - 2008 - elibrary.ru
В монографии проанализированы основные концепции о природе старения, история
их возникновения и эволюция. Изложены современные представления о …

Melatonin as a key regulator in seed germination under abiotic stress

L Wang, M Tanveer, H Wang… - Journal of Pineal …, 2024 - Wiley Online Library
Seed germination (SG) is the first stage in a plant's life and has an immense importance in
sustaining crop production. Abiotic stresses reduce SG by increasing the deterioration of …

Melatonin: action as antioxidant and potential applications in human disease and aging

D Bonnefont-Rousselot, F Collin - Toxicology, 2010 - Elsevier
This review aims at describing the beneficial properties of melatonin related to its antioxidant
effects. Oxidative stress, ie, an imbalance between the production of reactive oxygen …

Melatonin ameliorates H2O2-induced oxidative stress through modulation of Erk/Akt/NFkB pathway

M Moniruzzaman, I Ghosal, D Das, SB Chakraborty - Biological Research, 2018 - Springer
Background Improper control on reactive oxygen species (ROS) elimination process and
formation of free radicals causes tissue dysfunction. Pineal hormone melatonin is …