Host genetics in susceptibility to and severity of mycobacterial diseases

AS Apt, NN Logunova, TK Kondratieva - Tuberculosis, 2017 - Elsevier
The genetic analysis of susceptibility to infections has proven to be extremely useful for
identification of key cells, molecules, pathways, and genes involved in the battle between …

Effects of AANAT overexpression on the inflammatory responses and autophagy activity in the cellular and transgenic animal levels

J Tao, M Yang, H Wu, T Ma, C He, M Chai, X Zhang… - Autophagy, 2018 - Taylor & Francis
To explore the anti-inflammatory activity of endogenous produced melatonin, a melatonin-
enriched animal model (goat) with AANAT transfer was successfully generated with somatic …

肉牛种业科技创新发展现状与趋势分析

张天留, 葛菲, 朱波, 高会江, 李俊雅, 高雪 - 中国畜禽种业, 2022 - xq.aiijournal.com
良种对肉牛业发展的贡献率达40%, 为牛肉产品稳产保供提供了关键支撑,
而科技创新是引领肉牛种业高质量发展的基础和关键. 因此, 该文立足“十四五” 面向“十五五” …

Improved expression of green fluorescent protein in cattle embryos produced by ICSI-mediated gene transfer with spermatozoa treated with streptolysin-O

E Sánchez-Villalba, ME Arias, P Loren… - Animal reproduction …, 2018 - Elsevier
The ICSI-sperm mediated gene transfer (ICSI-SMGT) has been used to produce transgenic
mice with high efficiency; however, the efficiency of this technique in farm animals is still less …

Strategies for transfection of bovine mesenchymal stem cells with pBC1-anti-CD3 vector

FB Duarte, MM Brígido, EO Melo, SN Báo… - Animal …, 2022 - Taylor & Francis
Cells from different origins behave differently regarding the incorporation of exogenous DNA
and formation of transgenic cells. Milk production of recombinant antibody may benefit from …

[HTML][HTML] Sp110 enhances macrophage resistance to Mycobacterium tuberculosis via inducing endoplasmic reticulum stress and inhibiting anti-apoptotic factors

Y Wu, Z Guo, F Liu, K Yao, M Gao, Y Luo, Y Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Tuberculosis remains a leading health problem worldwide and still accounts for about 1.3
million deaths annually. Expression of the mouse Sp110 nuclear body protein (Sp110) …

Dynamic replacement of H3. 3 affects nuclear reprogramming in early bovine SCNT embryos

Y Wang, Y Li, D Luan, J Kang, R He, Y Zhang, F Quan - Theriogenology, 2020 - Elsevier
The histone variant H3. 3 is an important maternal factor in fertilization of oocytes and
reprogramming of somatic cell nuclear transfer (SCNT) embryos. As a crucial replacement …

Cell viability of bovine spermatozoa subjected to DNA electroporation and DNAse I treatment

PV Cavalcanti, MP Milazzotto, R Simões, M Nichi… - Theriogenology, 2016 - Elsevier
Many mechanisms involved in sperm-mediated gene transfer (SMGT) are still unknown. It is
still a matter of debate whether exogenous DNA fragments incorporated by the embryo are …

Growth performance, reproductive traits and offspring survivability of genetically modified rams overexpressing toll-like receptor 4

YC Yao, HB Han, XT Song, SL Deng, YF Liu, MH Lu… - Theriogenology, 2017 - Elsevier
Genetic modification provides a means to enhancing disease resistance in animals. Toll-like
receptor 4 (TLR4), a member of the TLR family, is critical for the recognition of …

Characterization of promoter of the tuberculosis-resistant gene intracellular pathogen resistance 1

Y Wu, F Liu, Y Zhang, Y Wang, Z Guo, Y Zhang - Immunologic research, 2016 - Springer
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which most
commonly affects the lungs and causes over 1.3 million people die annually. Variation in …