Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions

P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

Green chemistry meets asymmetric organocatalysis: a critical overview on catalysts synthesis

A Antenucci, S Dughera, P Renzi - ChemSusChem, 2021 - Wiley Online Library
Can green chemistry be the right reading key to let organocatalyst design take a step
forward towards sustainable catalysis? What if the intriguing chemistry promoted by more …

Recent advances in the asymmetric synthesis of pharmacology-relevant nitrogen heterocycles via stereoselective aza-Michael reactions

MG Vinogradov, OV Turova, SG Zlotin - Organic & Biomolecular …, 2019 - pubs.rsc.org
The prevalence of nitrogen containing heterocycles in natural products and pharmaceuticals
is a doubtless fact. In this review, recent applications of a stereoselective aza-Michael …

Synthesis of amides from acid chlorides and amines in the bio-based solvent Cyrene™

TW Bousfield, KPR Pearce, SB Nyamini… - Green …, 2019 - pubs.rsc.org
Cyrene™ as a bio-alternative dipolar aprotic solvent: a waste minimizing and molar efficient
protocol for the synthesis of amides from acid chlorides and primary amines in the bio …

[HTML][HTML] Recent advances in asymmetric organocatalyzed conjugate additions to nitroalkenes

DA Alonso, A Baeza, R Chinchilla, C Gómez… - Molecules, 2017 - mdpi.com
The asymmetric conjugate addition of carbon and heteroatom nucleophiles to nitroalkenes
is a very interesting tool for the construction of highly functionalized synthetic building …

Bifunctional tertiary amine-squaramide catalyzed asymmetric catalytic 1, 6-conjugate addition/aromatization of para-quinone methides with oxindoles

YH Deng, XZ Zhang, KY Yu, X Yan, JY Du… - Chemical …, 2016 - pubs.rsc.org
The asymmetric catalytic 1, 6-addition of p-QMs with racemic oxindoles under the
bifunctional catalysis of C2-symmetric dimeric Cinchona-derived squaramide is described …

Enantioselective S− H Insertion Reactions of α‐Carbonyl Sulfoxonium Ylides

PB Momo, AN Leveille, EHE Farrar… - Angewandte …, 2020 - Wiley Online Library
The first example of enantioselective S− H insertion reactions of sulfoxonium ylides is
reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to …

[HTML][HTML] A robust and tunable halogen bond organocatalyzed 2-deoxyglycosylation involving quantum tunneling

C Xu, VUB Rao, J Weigen, CCJ Loh - Nature communications, 2020 - nature.com
The development of noncovalent halogen bonding (XB) catalysis is rapidly gaining traction,
as isolated reports documented better performance than the well-established hydrogen …

Enantioselective indole insertion reactions of α-carbonyl sulfoxonium ylides

AN Leveille, R Echemendía, AE Mattson… - Organic …, 2021 - ACS Publications
The first example of organocatalytic enantioselective C–H insertion reactions of indoles and
sulfoxonium ylides is reported. Under the influence of phosphoric acid catalysis, levels of …

Asymmetric Total Synthesis of Apocynaceae Hydrocarbazole Alkaloids (+)-Deethylibophyllidine and (+)-Limaspermidine

JY Du, C Zeng, XJ Han, H Qu, XH Zhao… - Journal of the …, 2015 - ACS Publications
An unprecedented asymmetric catalytic tandem aminolysis/aza-Michael addition reaction of
spirocyclic para-dienoneimides has been designed and developed through organocatalytic …