The discovery of the endocannabinoid system, comprising the G‐protein coupled
cannabinoid 1 and 2 receptors (CB 1/2), their endogenous lipid ligands or …

The mammalian body has a highly developed immune system which guards against
continuous invading protein attacks and aims at preventing, attenuating or repairing the …

Monocyte chemotactic protein-1 (MCP-1)(also referred to as chemokine (CC motif) ligand 2
(CCL2) is expressed by mainly inflammatory cells and endothelial cells. The expression …

Objectives The anti-inflammatory effects of O-1602 and cannabidiol (CBD), the ligands of G
protein–coupled receptor 55 (GPR55), on experimental acute pancreatitis (AP) were …

Background Various factors trigger the inflammatory response and cytokine activation in
skeletal muscle. Inflamed muscle will exhibit significant levels of inflammation and cytokine …

Background: Endocannabinoid 2-arachidonoylglycerol (2-AG) is an anti-nociceptive lipid
that is inactivated through cellular uptake and subsequent catabolism by monoacylglycerol …

The endocannabinoid system has been shown to mediate beneficial effects on
gastrointestinal inflammation via cannabinoid receptors 1 (CB1) and 2 (CB2). These …

AIM To investigate the anti-inflammatory effect and the possible mechanisms of an agonist of
cannabinoid (CB) receptors, WIN55-212-2 (WIN55), in mice with experimental colitis, so as …

Although severe abdominal pain is the main symptom of acute pancreatitis, its mechanisms
are poorly understood. An emerging body of literature evidence indicates that neurogenic …

Background Pancreatitis is an increasingly common clinical condition that causes significant
morbidity and mortality. Cannabis use causes conflicting effects on pancreatitis …