ETS-related gene (ERG) is a member of the E-26 transformation-specific (ETS) family of
transcription factors with roles in development that include vasculogenesis, angiogenesis …

The Ets family of transcription factors characterized by an evolutionarily-conserved DNA-
binding domain regulates expression of a variety of viral and cellular genes by binding to a …

Background Friend leukemia virus integration 1 (FLI1), an ETS transcription factor family
member, acts as an oncogenic driver in hematological malignancies and promotes tumor …

Microvascular endothelial cells (ECs) within different tissues are endowed with distinct but
as yet unrecognized structural, phenotypic, and functional attributes. We devised EC …

The Ets1 proto-oncoprotein is a member of the Ets family of transcription factors that share a
unique DNA binding domain, the Ets domain. The DNA binding activity of Ets1 is controlled …

The transcription factors that regulate endothelial cell development have been a focus of
active research for several years, and many players in the endothelial transcriptional …

Vascular development begins when mesodermal cells differentiate into endothelial cells,
which then form primitive vessels. It has been hypothesized that endothelial-specific gene …

Chromosomal rearrangements that result in high level expression of ETS gene family
members are common events in human prostate cancer. Most frequently, the androgen …

The Ets1 transcription factor is a member of the Ets gene family and is highly conserved
throughout evolution. Ets1 is known to regulate a number of important biological processes …

Tumor-associated chromosomal translocations lead to the formation of chimeric fusions
between the EWS gene and one of five different ETS transcription factors in Ewing's family …