The suprachiasmatic nucleus: a 25-year retrospective

DR Weaver - Journal of biological rhythms, 1998 - journals.sagepub.com
The suprachiasmatic nuclei (SCN) of the anterior hypothalamus contain the master circadian
pacemaker in mammals. On the occasion of the 25th anniversary of the discovery of the …

The circadian visual system, 2005

LP Morin, CN Allen - Brain research reviews, 2006 - Elsevier
The primary mammalian circadian clock resides in the suprachiasmatic nucleus (SCN), a
recipient of dense retinohypothalamic innervation. In its most basic form, the circadian …

Distinct roles for GABA across multiple timescales in mammalian circadian timekeeping

D DeWoskin, J Myung, MDC Belle… - Proceedings of the …, 2015 - National Acad Sciences
The suprachiasmatic nuclei (SCN), the central circadian pacemakers in mammals, comprise
a multiscale neuronal system that times daily events. We use recent advances in graphics …

The circadian visual system

LP Morin - Brain Research Reviews, 1994 - Elsevier
The retina transduces photic stimuli and transmits that information centrally for further
processing. This review emphasizes the fact that the nervous system components governing …

The dynamics of GABA signaling: revelations from the circadian pacemaker in the suprachiasmatic nucleus

HE Albers, JC Walton, KL Gamble, JK McNeill IV… - Frontiers in …, 2017 - Elsevier
Virtually every neuron within the suprachiasmatic nucleus (SCN) communicates via
GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a …

Chronobiotics—drugs that shift rhythms

D Dawson, SM Armstrong - Pharmacology & therapeutics, 1996 - Elsevier
A chronobiotic is defined and levels of action within the mammalian circadian pacemaker
system, such as the retina, retinohypothalamic tract, geniculohypothalamic tract …

A benzodiazepine used in the treatment of insomnia phase-shifts the mammalian circadian clock

FW Turek, S Losee-Olson - Nature, 1986 - nature.com
Between 5 and 20% of the adult population in Western countries suffer from insufficient
and/or unsatisfying sleep1, 2, often associated with certain psychiatric disorders or with …

Serotonin and the mammalian circadian system: I. In vitro phase shifts by serotonergic agonists and antagonists

RA Prosser, RR Dean, DM Edgar… - Journal of …, 1993 - journals.sagepub.com
The primary mammalian circadian clock, located in the suprachiasmatic nuclei (SCN),
receives a major input from the raphe nuclei. The role of this input is largely unknown, and is …

Lesions of the thalamic intergeniculate leaflet alter hamster circadian rhythms

ME Harrington, B Rusak - Journal of biological rhythms, 1986 - journals.sagepub.com
We have investigated the effects of destruction of the geniculo-hypothalamic tract (GHT) on
the circadian system of golden hamsters. In the first experiment, intact hamsters were …

Neurochemical organization of circadian rhythm in the suprachiasmatic nucleus

SIT Inouye, S Shibata - Neuroscience research, 1994 - Elsevier
The circadian rhythm in mammals is under control of the pacemaker located in the
suprachiasmatic nucleus (SCN) of the hypothalamus. This tiny nucleus contains a number of …