Candidate glaucoma biomarkers: From proteins to metabolites, and the pitfalls to clinical applications
AFV Cueto, L Álvarez, M García, A Álvarez-Barrios… - Biology, 2021 - mdpi.com
Simple Summary Glaucoma is a devastating eye disease causing progressive vision loss
and consequent irreversible blindness. The global prevalence of glaucoma is estimated at …
and consequent irreversible blindness. The global prevalence of glaucoma is estimated at …
ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies
Label-free quantification (LFQ) with a specific and sequentially integrated workflow of
acquisition technique, quantification tool and processing method has emerged as the …
acquisition technique, quantification tool and processing method has emerged as the …
[HTML][HTML] The aqueous humor proteome of primary open angle glaucoma: an extensive review
WHG Hubens, RJC Mohren, I Liesenborghs… - Experimental Eye …, 2020 - Elsevier
Background We reviewed the literature on the aqueous humor (AH) proteome of primary
open angle glaucoma (POAG) patients in order to obtain deeper insight into the …
open angle glaucoma (POAG) patients in order to obtain deeper insight into the …
Insights into the regulatory molecules involved in glaucoma pathogenesis
Glaucoma is an important cause of irreversible blindness, characterized by optic nerve
anomalies. Increased intraocular pressure (IOP) and aging are major risk factors. Retinal …
anomalies. Increased intraocular pressure (IOP) and aging are major risk factors. Retinal …
Oxidative stress induced dysfunction of protein synthesis in 661w mice photoreceptor cells
Photoreceptor cells are highly susceptible to oxidative-stress-induced damage due to their
high metabolic rate. Oxidative stress plays a key role in driving pathological events in …
high metabolic rate. Oxidative stress plays a key role in driving pathological events in …
Low expression of GSTP1 in the aqueous humour of patients with primary open‐angle glaucoma
A Liu, L Wang, Q Feng, D Zhang… - Journal of Cellular …, 2021 - Wiley Online Library
Primary open‐angle glaucoma (POAG) is characterized by irreversible neurodegeneration
accompanied by visual field defects and high intraocular pressure. Currently, an effective …
accompanied by visual field defects and high intraocular pressure. Currently, an effective …
[HTML][HTML] Proteome alterations in aqueous humour of primary open angle glaucoma patients
H Liu, F Anders, S Funke, K Mercieca… - International Journal …, 2020 - ncbi.nlm.nih.gov
AIM To unravel the primary open angle glaucoma (POAG) related proteomic changes in
aqueous humour (AH). METHODS Totally 35 patients listed for cataract surgery (controls: n …
aqueous humour (AH). METHODS Totally 35 patients listed for cataract surgery (controls: n …
Proteome characterization of glaucoma aqueous humor
X Liu, X Liu, Y Wang, H Sun, Z Guo, X Tang, J Li… - Molecular & Cellular …, 2021 - ASBMB
Glaucoma is the leading cause of irreversible blindness worldwide. The proteome
characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 …
characterization of glaucoma is not clearly understood. A total of 175 subjects, including 57 …
Potential Immune-Inflammatory Proteome Biomarkers for Guiding the Treatment of Patients with Primary Acute Angle-Closure Glaucoma Caused by COVID-19
Q Gong, M Fu, J Wang, S Zhao… - Journal of Proteome …, 2024 - ACS Publications
Primary acute angle-closure glaucoma (PAACG) is a sight-threatening condition that can
lead to blindness. With the increasing incidence of COVID-19, a multitude of people are …
lead to blindness. With the increasing incidence of COVID-19, a multitude of people are …
Detection of proteins associated with extracellular matrix regulation in the aqueous humour of patients with primary glaucoma
Purpose The protein composition of aqueous humour (AH) has held significant relevance
and remains to be the prime sample in the discovery of biomarkers in glaucoma. The …
and remains to be the prime sample in the discovery of biomarkers in glaucoma. The …