Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Skin tissue regeneration for burn injury

A Shpichka, D Butnaru, EA Bezrukov… - Stem cell research & …, 2019 - Springer
The skin is the largest organ of the body, which meets the environment most directly. Thus,
the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a …

Advances of stem cell therapeutics in cutaneous wound healing and regeneration

S Kanji, H Das - Mediators of inflammation, 2017 - Wiley Online Library
Cutaneous wound healing is a complex multiple phase process, which overlaps each other,
where several growth factors, cytokines, chemokines, and various cells interact in a well …

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

Y Imaizumi, Y Okada, W Akamatsu, M Koike… - Molecular brain, 2012 - Springer
Background Parkinson's disease (PD) is a neurodegenerative disease characterized by
selective degeneration of dopaminergic neurons in the substantia nigra (SN). The familial …

Neural crest stem cells: discovery, properties and potential for therapy

A Achilleos, PA Trainor - Cell research, 2012 - nature.com
Neural crest (NC) cells are a migratory cell population synonymous with vertebrate
evolution. They generate a wide variety of cell and tissue types during embryonic and adult …

The future of regenerative medicine: cell therapy using pluripotent stem cells and acellular therapies based on extracellular vesicles

M Jarrige, E Frank, E Herardot, S Martineau, A Darle… - Cells, 2021 - mdpi.com
The rapid progress in the field of stem cell research has laid strong foundations for their use
in regenerative medicine applications of injured or diseased tissues. Growing evidences …

Derivation of mesenchymal stromal cells from pluripotent stem cells through a neural crest lineage using small molecule compounds with defined media

M Fukuta, Y Nakai, K Kirino, M Nakagawa, K Sekiguchi… - PloS one, 2014 - journals.plos.org
Neural crest cells (NCCs) are an embryonic migratory cell population with the ability to
differentiate into a wide variety of cell types that contribute to the craniofacial skeleton …

Connecting the dots: melanoma cell of origin, tumor cell plasticity, trans‐differentiation, and drug resistance

E Castro‐Pérez, M Singh, S Sadangi… - Pigment Cell & …, 2023 - Wiley Online Library
Melanoma, a lethal malignancy that arises from melanocytes, exhibits a multiplicity of clinico‐
pathologically distinct subtypes in sun‐exposed and non‐sun‐exposed areas. Melanocytes …

[HTML][HTML] Immunological aspects of RPE cell transplantation

S Sugita, M Mandai, H Kamao, M Takahashi - Progress in retinal and eye …, 2021 - Elsevier
Retinal pigment epithelial (RPE) cells have several functions, including support of the neural
retina and choroid in the eye and immunosuppression. Cultured human RPE cells directly …

A human Dravet syndrome model from patient induced pluripotent stem cells

N Higurashi, T Uchida, C Lossin, Y Misumi, Y Okada… - Molecular brain, 2013 - Springer
Background Dravet syndrome is a devastating infantile-onset epilepsy syndrome with
cognitive deficits and autistic traits caused by genetic alterations in SCN1A gene encoding …