In Europe, neuropsychiatric diseases currently make up approximately a third of the total
burden of disease. In 2004, 27% of the overall population was affected by at least one of the …

Iron is an essential element involved in a multitude of bodily processes. It is tightly regulated,
as elevated deposition in tissues is associated with diseases such as multiple sclerosis …

Background Multiple sclerosis (MS) is a common demyelinating disease of the central
nervous system. Although the exact pathogenesis remains unknown, the leading theory is …

Background: Damage to the myelin sheath (demyelination) is one of the main manifestations
of multiple sclerosis (MS). Interestingly, both MS and vitamin B deficiencies result in severe …

Background: Multiple sclerosis (MS) is associated with changes in quality of life, disability,
fatigue and anthropometric measurements. The important relationship of dietary patterns …

Oligodendrocytes not only produce myelin to facilitate nerve impulse conduction, but are
also essential metabolic partners of the axon. Oligodendrocyte loss and myelin destruction …

Background Although the most common clinical presentation of multiple sclerosis (MS) is the
so called Relapsing-Remitting MS (RRMS), the molecular mechanisms responsible for its …

Background: Hyperhomocysteinemia, vitamin B12 and folate deficiency have been linked to
cognitive dysfunction in multiple sclerosis (MS) patients. Objective: This study aimed to …

Iron uptake, utilisation, release and storage occur at the gene level. Individuals with variant
forms of genes involved in iron metabolism may have different requirements for iron and are …

The previously reported link between homocysteine and obesity, both identified as
established risk factors for multiple sclerosis (MS), has not previously been studied in …