An update on cognitive frailty: Its definition, impact, associated factors and underlying mechanisms, and interventions

T Sugimoto, H Arai, T Sakurai - Geriatrics & gerontology …, 2022 - Wiley Online Library
Since the concept and operational definition of “cognitive frailty”(simultaneous presence of
physical frailty and cognitive impairment without concurrent dementia) were proposed by the …

Brain renin–angiotensin system at the intersect of physical and cognitive frailty

C Cosarderelioglu, LS Nidadavolu… - Frontiers in …, 2020 - frontiersin.org
The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Integrated care for older people screening tool for measuring intrinsic capacity: preliminary findings from ICOPE pilot in China

L Ma, JK Chhetri, Y Zhang, P Liu, Y Chen, Y Li… - Frontiers in …, 2020 - frontiersin.org
Objectives: The World Health Organization (WHO) proposed the Integrated Care for Older
People (ICOPE) screening tool to identify older people with priority conditions associated …

[HTML][HTML] Understanding the physiological links between physical frailty and cognitive decline

L Ma, P Chan - Aging and disease, 2020 - ncbi.nlm.nih.gov
Declines in both physical and cognitive function are associated with increasing age.
Understanding the physiological link between physical frailty and cognitive decline may …

A comparative investigation of machine learning algorithms for predicting safety signs comprehension based on socio-demographic factors and cognitive sign features

S Rostamzadeh, A Abouhossein, M Saremi, F Taheri… - Scientific Reports, 2023 - nature.com
This study examines whether the socio-demographic factors and cognitive sign features can
be used for envisaging safety signs comprehensibility using predictive machine learning …

Recent advances in research on Alzheimer's disease in China

Y Zhang, Y Li, L Ma - Journal of clinical neuroscience, 2020 - Elsevier
China has the largest number of individuals with dementia worldwide. Alzheimer's disease
(AD) is a growing global health issue that seriously threatens human health and quality of …

Frailty and hypertension in older adults: current understanding and future perspectives

P Liu, Y Li, Y Zhang, SE Mesbah, T Ji, L Ma - Hypertension Research, 2020 - nature.com
Hypertension is an important factor affecting the health of older adults. Antihypertensives
can reduce stroke, cardiovascular events, and mortality in older hypertensive patients. Blood …

[HTML][HTML] Cohort profile: West China health and aging trend (WCHAT)

L Hou, X Liu, Y Zhang, W Zhao, X Xia, X Chen… - The Journal of nutrition …, 2021 - Elsevier
Abstract Objectives The West China Health and Aging Trends study (WCHAT) is intended to
focus on the research that will guide efforts to reduce disability, maximize health and …

The mediating effect of psychological distress on cognitive function and physical frailty among the elderly: evidence from rural Shandong, China

Z Jing, J Li, Y Wang, L Ding, X Tang, Y Feng… - Journal of affective …, 2020 - Elsevier
Background Few studies have explored the underlying mechanism between physical frailty
and cognitive function. The aim of this study is to explore the mediating role of psychological …

Epidemiological characteristics and related factors of frailty in older Chinese adults with hypertension: a population-based study

L Ma, JK Chhetri, P Liu, T Ji, L Zhang… - Journal of …, 2020 - journals.lww.com
Objectives: Hypertension is highly prevalent in the elderly and represents a major risk factor
for cardiovascular complications such as coronary heart disease, stroke, and cognitive …