MicroRNAs in prostate cancer: Functional role as biomarkers

R Kanwal, AR Plaga, X Liu, GC Shukla, S Gupta - Cancer Letters, 2017 - Elsevier
MicroRNAs (miRNAs) are small endogenous non-coding molecules that alters gene
expression through post-transcriptional regulation of messenger RNA. Compelling evidence …

Understanding epigenetic effects of endocrine disrupting chemicals: from mechanisms to novel test methods

A Alavian‐Ghavanini, J Rüegg - Basic & clinical pharmacology …, 2018 - Wiley Online Library
Endocrine‐disrupting chemicals (EDC s) are man‐made chemicals that interfere with
hormonal signalling pathways. They are used in, for example, production of common …

[HTML][HTML] MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer

F Ghamlouche, A Yehya, Y Zeid, H Fakhereddine… - Translational …, 2023 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed cancers among men
worldwide. Despite the presence of accumulated clinical strategies for PCa management …

Crosstalk between miRNAs and DNA Methylation in Cancer

M Saviana, P Le, L Micalo, D Del Valle-Morales… - Genes, 2023 - mdpi.com
miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

[HTML][HTML] An overview of prostate cancer (PCa) diagnosis: Potential role of miRNAs

M Bilal, A Javaid, F Amjad, T Abou Youssif… - Translational Oncology, 2022 - Elsevier
Prostate cancer is the second most frequently diagnosed cancer among men worldwide,
with the estimated sixth leading cause of cancer death. Despite major advancements in …

The microRNA lifecycle in health and cancer

LA de Rooij, DJ Mastebroek, N Ten Voorde… - Cancers, 2022 - mdpi.com
Simple Summary MicroRNAs (miRNAs) regulate messenger RNA (mRNA) expression at the
post-transcriptional level. They play an important role within physiological and pathological …

Glycolysis-related gene expression profiling serves as a novel prognosis risk predictor for human hepatocellular carcinoma

L Zhang, Y Li, Y Dai, D Wang, X Wang, Y Cao, W Liu… - Scientific Reports, 2021 - nature.com
Metabolic pattern reconstruction is an important factor in tumor progression. Metabolism of
tumor cells is characterized by abnormal increase in anaerobic glycolysis, regardless of high …

Tribbles-1 expression and its function to control inflammatory cytokines, including interleukin-8 levels are regulated by miRNAs in macrophages and prostate cancer …

C Niespolo, JM Johnston, SR Deshmukh… - Frontiers in …, 2020 - frontiersin.org
The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP
kinase activation and mediating protein degradation via the COP1 ubiquitin ligase. TRIB1 …

Intrinsically disordered region-mediated condensation of IFN-inducible SCOTIN/SHISA-5 inhibits ER-to-Golgi vesicle transport

N Kim, TH Kim, C Kim, JE Lee, MG Kang, S Shin… - Developmental Cell, 2023 - cell.com
Newly synthesized proteins in the endoplasmic reticulum (ER) are sorted by coat protein
complex II (COPII) at the ER exit site en route to the Golgi. Under cellular stresses, COPII …

MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

D Barros-Silva, P Costa-Pinheiro, H Duarte… - Cell death & …, 2018 - nature.com
Upregulation of MYC and miRNAs deregulation are common in prostate cancer (PCa).
Overactive MYC may cause miRNAs' expression deregulation through transcriptional and …