Global status of phenotypic pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates: an updated systematic review and meta-analysis

Z Wang, Z Tang, H Heidari, L Molaeipour… - Journal of …, 2023 - Taylor & Francis
Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of
action active against multidrug-resistant-TB (MDR-TB). Thus, the aim of updated meta …

Epidemiological study of mycobacterium tuberculosis in Baghdad governorate, Iraq

AAJ Aljanaby, QMH Al-Faham, IAJ Aljanaby, TH Hasan - Gene Reports, 2022 - Elsevier
Abstract Background & objective Mycobacterium Tuberculosis (Mtb) is one of the most gram
positive dangerous pathogenic bacteria cause tuberculosis (TB) and cause hundreds …

Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan

AS Khan, JE Phelan, MT Khan, S Ali, M Qasim… - Scientific reports, 2021 - nature.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is endemic in Pakistan.
Resistance to both firstline rifampicin and isoniazid drugs (multidrug-resistant TB; MDR-TB) …

[HTML][HTML] MDR-TB in Pakistan: Challenges, efforts, and recommendations

MA Khan, W Bilal, H Asim, ZS Rahmat, MY Essar… - Annals of Medicine and …, 2022 - Elsevier
Tuberculosis (TB), a global health concern is also a leading cause of mortality and morbidity
across Pakistan affecting a major proportion of the population. The absence of an integrated …

[HTML][HTML] Distribution of common and rare drug resistance patterns in Mycobacterium tuberculosis clinical isolates revealed by GenoType MTBDRplus and MTBDRsl …

Z Khan, Y Zhu, P Guan, J Peng, B Su, S Ma… - Journal of Thoracic …, 2023 - ncbi.nlm.nih.gov
Background Tuberculosis (TB) remains a significant global health emergency caused by
Mycobacterium tuberculosis (Mtb). The epidemiology, transmission, genotypes, mutational …

Antimicrobial use among hospitalized neonates and children; findings and implications from a comprehensive point prevalence survey among general tertiary …

ZU Mustafa, M Salman, AH Khan… - Infection and Drug …, 2024 - Taylor & Francis
Purpose Antimicrobial resistance is a global health crisis exacerbated by excessive and
inappropriate use of antibiotics, especially among low-and middle-income countries …

Evaluation of time to sputum smear conversion and its association with treatment outcomes among drug-resistant tuberculosis patients: a retrospective record …

AI Alzarea, A Saifullah, YH Khan, AS Alanazi… - Frontiers in …, 2024 - frontiersin.org
Background: This study examined the time to sputum smear and culture conversion and
determinants of conversion, as well as variables associated with treatment outcomes among …

[HTML][HTML] Cervical Pott's disease presenting as quadriplegia in a young patient: a case report

SR Khan, A Ahmad, M Saqib, M Iftikhar - Cureus, 2023 - ncbi.nlm.nih.gov
Cervical Pott's disease, a form of spinal tuberculosis (TB), is a significant concern in low-and
middle-income countries (LMICs). Early detection and treatment are critical to preventing …

Potential and weak links in the management of tuberculosis by Pakistani private pharmacy staff

F Balquis, MF Sohail, H Hamid, W Ullah… - Frontiers in Public …, 2023 - frontiersin.org
Introduction The emergence of MDR-TB is a global threat and an obstacle to the effective
control of TB in Pakistan. A lack of proper TB knowledge among the staff in private …

Silver nanoparticles as a nanoprobe for trace level simultaneous detection of streptomycin sulfate and isoniazid and anti-TB activity of their nanoparticles complexes

SS Naqvi, H Anwar, MY Noori, A Siddiqui, Z Ali… - Journal of Molecular …, 2023 - Elsevier
A facile method was developed for the simultaneous detection of two anti-TB drugs (ie,
streptomycin sulfate and isoniazid) by using maltol capped silver nanoparticles (McAgNPs) …