Local force and geometry sensing regulate cell functions
V Vogel, M Sheetz - Nature reviews Molecular cell biology, 2006 - nature.com
The shapes of eukaryotic cells and ultimately the organisms that they form are defined by
cycles of mechanosensing, mechanotransduction and mechanoresponse. Local sensing of …
cycles of mechanosensing, mechanotransduction and mechanoresponse. Local sensing of …
Steered molecular dynamics and mechanical functions of proteins
Atomic force microscopy of single molecules, steered molecular dynamics and the theory of
stochastic processes have established a new field that investigates mechanical functions of …
stochastic processes have established a new field that investigates mechanical functions of …
ForceGen: End-to-end de novo protein generation based on nonlinear mechanical unfolding responses using a language diffusion model
Through evolution, nature has presented a set of remarkable protein materials, including
elastins, silks, keratins and collagens with superior mechanical performances that play …
elastins, silks, keratins and collagens with superior mechanical performances that play …
NAMD2: greater scalability for parallel molecular dynamics
Molecular dynamics programs simulate the behavior of biomolecular systems, leading to
understanding of their functions. However, the computational complexity of such simulations …
understanding of their functions. However, the computational complexity of such simulations …
[图书][B] The chemical bond in inorganic chemistry: the bond valence model
ID Brown - 2016 - books.google.com
The bond valence model, a description of acid-base bonding, is widely used for analysing
and modelling the structures and properties of solids and liquids. Unlike other models of …
and modelling the structures and properties of solids and liquids. Unlike other models of …
Molecular mechanistic origin of the toughness of natural adhesives, fibres and composites
Natural materials are renowned for their strength and toughness,,,,. Spider dragline silk has
a breakage energy per unit weight two orders of magnitude greater than high tensile steel …
a breakage energy per unit weight two orders of magnitude greater than high tensile steel …
Conformational transition of SARS-CoV-2 spike glycoprotein between its closed and open states
In 2020, the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
infected millions of people worldwide and caused the coronavirus disease 2019 (COVID …
infected millions of people worldwide and caused the coronavirus disease 2019 (COVID …
Covalent mechanochemistry: theoretical concepts and computational tools with applications to molecular nanomechanics
J Ribas-Arino, D Marx - Chemical reviews, 2012 - ACS Publications
In the following section, we will recapitulate selected experimental milestones through the
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …
eyes of the theoretician, which, in our opinion, significantly advanced the field of covalent …
Mechanical and chemical unfolding of a single protein: a comparison
M Carrion-Vazquez, AF Oberhauser… - Proceedings of the …, 1999 - National Acad Sciences
Is the mechanical unraveling of protein domains by atomic force microscopy (AFM) just a
technological feat or a true measurement of their unfolding? By engineering a protein made …
technological feat or a true measurement of their unfolding? By engineering a protein made …
Persistent homology analysis of protein structure, flexibility, and folding
Proteins are the most important biomolecules for living organisms. The understanding of
protein structure, function, dynamics, and transport is one of the most challenging tasks in …
protein structure, function, dynamics, and transport is one of the most challenging tasks in …