Clostridium difficile is the main causative agent of antibiotic-associated and health care-
associated infective diarrhea. Recently, there has been growing interest in alternative …

Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Summary Background The control of Clostridium difficile infections is an international clinical
challenge. The incidence of C difficile in England declined by roughly 80% after 2006 …

There has been a startling shift in the epidemiology of Clostridium difficile infection over the
last decade worldwide, and it is now increasingly recognized as a cause of diarrhea in the …

Antibiotic-associated diarrhea (AAD) and Clostridum difficile infections (CDI) have been well
studied for adult cases, but not as well in the pediatric population. Whether the disease …

Background. Clostridium difficile has long been considered to be a nosocomial pathogen
but has emerged in the community in recent years. During infancy, asymptomatic C. difficile …

Clostridium difficile infection is the leading cause of diarrhoea in the industrialised world.
First identified in 1935, our knowledge about the clonal population structure, toxins and PCR …

The symptoms of Clostridium difficile infection are caused by toxins expressed from its 19 kb
pathogenicity locus (PaLoc). Stable integration of the PaLoc is suggested by its single …

Background Approximately 30–40% of children< 1 year of age are Clostridium difficile
colonized, and may represent a reservoir for adult C. difficile infections (CDI). Risk factors for …