Not all animals need a microbiome
It is often taken for granted that all animals host and depend upon a microbiome, yet this has
only been shown for a small proportion of species. We propose that animals span a …
only been shown for a small proportion of species. We propose that animals span a …
Contact lens-related corneal infection: Intrinsic resistance and its compromise
Contact lenses represent a widely utilized form of vision correction with more than 140
million wearers worldwide. Although generally well-tolerated, contact lenses can cause …
million wearers worldwide. Although generally well-tolerated, contact lenses can cause …
The gut-eye-lacrimal gland-microbiome axis in Sjögren Syndrome
The bacterial communities that collectively inhabit our body are called the microbiome.
Virtually all body surface harbors bacteria. Recent advances in next-generation sequencing …
Virtually all body surface harbors bacteria. Recent advances in next-generation sequencing …
Foundational concepts in the biology of bacterial keratitis
L Ung, J Chodosh - Experimental eye research, 2021 - Elsevier
Bacterial infections of the cornea, or bacterial keratitis (BK), are notorious for causing rapidly
fulminant disease and permanent vision loss, even among treated patients. In the last sixty …
fulminant disease and permanent vision loss, even among treated patients. In the last sixty …
Paradox of complex diversity: Challenges in the diagnosis and management of bacterial keratitis
Bacterial keratitis continues to be one of the leading causes of corneal blindness in the
developed as well as the developing world, despite swift progress since the dawn of the …
developed as well as the developing world, despite swift progress since the dawn of the …
Autoimmunity in dry eye disease–an updated review of evidence on effector and memory Th17 cells in disease pathogenicity
Abstract The classic Th1/Th2 dogma has been significantly reshaped since the subsequent
introduction of several new T helper cell subsets, among which the most intensively …
introduction of several new T helper cell subsets, among which the most intensively …
Current knowledge on the human eye microbiome: a systematic review of available amplicon and metagenomic sequencing data
H Delbeke, S Younas, I Casteels… - Acta …, 2021 - Wiley Online Library
Insights in the ocular surface microbiome are still at an early stage and many more
questions remain unanswered compared with other human‐associated microbial …
questions remain unanswered compared with other human‐associated microbial …
The ocular surface immune system through the eyes of aging
JG Galletti, CS de Paiva - The ocular surface, 2021 - Elsevier
Since the last century, advances in healthcare, housing, and education have led to an
increase in life expectancy. Longevity is accompanied by a higher prevalence of age-related …
increase in life expectancy. Longevity is accompanied by a higher prevalence of age-related …
A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation …
MME Metruccio, SJ Wan, H Horneman, AR Kroken… - The ocular …, 2019 - Elsevier
Purpose Contact lens wear carries a risk of complications, including corneal infection.
Solving these complications has been hindered by limitations of existing animal models …
Solving these complications has been hindered by limitations of existing animal models …
[HTML][HTML] Methodologic Considerations for Studying the Ocular Surface Microbiome
A Chowdhary, RN Van Gelder, M Sundararajan - Ophthalmology Science, 2023 - Elsevier
The ocular surface microbiome, unlike that of the skin or gut, has not been well
characterized. Culture experiments historically suggested a nearly sterile ocular surface, but …
characterized. Culture experiments historically suggested a nearly sterile ocular surface, but …