Despite great progress has been made in treatment strategies, colorectal cancer (CRC)
remains the predominant life-threatening malignancy with the feature of high morbidity and …

In-depth knowledge of cancer molecular and cellular mechanisms have revealed a strong
regulation of cancer development and progression by the inflammation which orchestrates …

Cytokine-based immunotherapy is a promising field in the cancer treatment, since cytokines,
as proteins of the immune system, are able to modulate the host immune response toward …

The tumor microenvironment (TME) plays a central role in tumor initiation, development,
immune escape, and clinical treatment. Hypoxia, an important characteristic of the TME …

Colorectal cancer (CRC) is the leading cause of cancer death worldwide. CRC therapeutic
strategies include surgical resection, chemotherapy, radiotherapy, and other approaches …

Colorectal cancer (CRC) is the third most diagnosed malignancy and the second leading
cause of cancer-related deaths worldwide. Locally advanced and metastatic disease exhibit …

Colorectal cancer, especially liver metastasis, is still a challenge worldwide. Traditional
treatment such as surgery, chemotherapy and radiotherapy have been difficult to be further …

Dendritic cells (DCs), the strongest antigen-presenting cells, are a focus for orchestrating the
immune system in the fight against cancer. Basic scientific investigations elucidating the …

Colorectal cancer (CRC) is one of the most frequent and deadly forms of cancer. About half
of patients are affected by metastasis, with the cancer spreading to eg, liver, lungs or the …

Colorectal cancer (CRC), a multi-step malignancy showing increasing incidence in today's
societies, represents an important worldwide health issue. Exogenous factors, such as …