The purpose of this review is to present the current state of the role of imaging in
photodynamic therapy (PDT). For the reader to fully appreciate the context of the discussions …

Porphyrinic molecules have a unique theranostic role in disease therapy; they have been
used to image, detect and treat different forms of diseased tissue including age-related …

Bladder cancer is a heterogeneous disease with a variable natural history. At one end of the
spectrum, low-grade Ta tumors have a low progression rate and require initial endoscopic …

Photodynamic therapy (PDT), also known as photoradiation therapy, phototherapy, or
photochemo-therapy, involves the use of a photoactive dye (photosensitizer) that is activated …

Light has been employed in the treatment of disease since antiquity. Many ancient
civilizations utilized phototherapy, but it was not until early last century that this form of …

Fluorescence-guided diagnostics is one of the most promising approaches for facile
detection of cancer in situ. Here we focus on β-galactosidase, which is overexpressed in …

Context Controversy exists regarding the therapeutic benefit and cost effectiveness of
photodynamic diagnosis (PDD) with 5-aminolevulinic acid (5-ALA) or hexyl aminolevulinate …

CONTEXT: The clinical benefit of photodynamic diagnosis (PDD) with 5-aminolevulinic acid
or hexaminolevulinate in addition to white-light cystoscopy (WLC) in bladder cancer has …

Objectives: The aim of this study was to assess the test performance and clinical
effectiveness of photodynamic diagnosis (PDD) compared with white light cystoscopy (WLC) …

Purpose: We compared hexaminolevulinate (Hexvix®) fluorescence cystoscopy with white
light cystoscopy for detecting carcinoma in situ. Materials and Methods: In this multicenter …