Green RP-HPLC method for simultaneous determination of sofosbuvir, ledipasvir, velpatasvir antivirals and beyond in their bulk material and co-formulated products
HM Mohamed, AS Saad, AM Morsi, HM Essam - Microchemical Journal, 2023 - Elsevier
In the present era, pharmaceutical industry is floated with the development of novel antiviral
medications either in single or co-formulated pills. This growth of antiviral drug market is …
medications either in single or co-formulated pills. This growth of antiviral drug market is …
[PDF][PDF] Bioanalytical method development and validation for the determination of sofosbuvir from human plasma
Objective: This study points to build up and validate a simple methodology to quantify the
most used drug sofosbuvir for the treatment of hepatitis C virus (HCV) infection, in human …
most used drug sofosbuvir for the treatment of hepatitis C virus (HCV) infection, in human …
Analytical profiling of sofosbuvir as NS5B protein inhibitor for oral drug delivery: Method development and Validation
SW Rangari, SB Bari - Bulletin of Faculty of Pharmacy Cairo …, 2022 - bfopcu.eg.net
Hepatitis C virus (HCV) non-structural protein 5B (NS5B), which is being studied for its RNA-
dependent RNA polymerase (RDRP). It has been demonstrated that the RDRP is highly …
dependent RNA polymerase (RDRP). It has been demonstrated that the RDRP is highly …
Validated reversed-phase liquid chromatographic method with gradient elution for simultaneous determination of the antiviral agents: sofosbuvir, ledipasvir …
E Ezzeldin, NF Abo-Talib, MH Tammam, YA Asiri… - Molecules, 2020 - mdpi.com
A simple, rapid, sensitive, and precise reversed-phase liquid chromatographic method was
developed and validated for the simultaneous determination of four direct-acting antivirals …
developed and validated for the simultaneous determination of four direct-acting antivirals …
[PDF][PDF] Simultaneous RP-HPLC method development and it's validation for estimation of sofosbuvir and velpatasvir in their combined dosage form
J Mamatha, N Devanna - Rasayan Journal of Chemistry, 2018 - rasayanjournal.co.in
ABSTRACT A new simple and precise simultaneous RP-HPLC method was developed and
validated for the identification and analysis of fixed dose combination of Sofosbuvir and …
validated for the identification and analysis of fixed dose combination of Sofosbuvir and …
Simultaneous quantification of simeprevir sodium: A hepatitis C protease inhibitor in binary and ternary mixtures with sofosbuvir and/or ledipasvir utilizing direct and H …
SH Mohamed, YM Issa, AI Salim - … Acta Part A: Molecular and Biomolecular …, 2019 - Elsevier
Simeprevir sodium (SMV); a novel hepatitis C inhibitor, quells hepatitis C viral replication by
binding to and repressing the protease, hepatitis C infection (HCV) NS3/4A. In this way, it is …
binding to and repressing the protease, hepatitis C infection (HCV) NS3/4A. In this way, it is …
[PDF][PDF] Development and validation of a stability-Indicating RP-HPLC method for simultaneous estimation of sofosbuvir and velpatasvir in fixed dose combination …
A simple, specific, sensitive, robust, accurate and precise reverse-phase high performance
liquid chromatographic (RP-HPLC) method was developed and validated for simultaneous …
liquid chromatographic (RP-HPLC) method was developed and validated for simultaneous …
[PDF][PDF] Development and validation of RPHPLC and UV spectroscopy methods for simultaneous estimation of Sofosbuvir and Ledipasvir in their combined tablet …
SY Rai, Y Prajapati, P Patni - An International journal of …, 2017 - pharmasm.com
The present research work describes a simple, accurate, precise and effective UV-Vis
Spectroscopic and RP-HPLC method for simultaneous estimation of Sofosbuvir and …
Spectroscopic and RP-HPLC method for simultaneous estimation of Sofosbuvir and …
UV-spectrophotometric and stability indicating RP-HPLC methods for the determination of the hepatitis C virus inhibitor Sofosbuvir in tablet dosage form
MEM Hassouna, MA Mohamed - Analytical Chemistry Letters, 2018 - Taylor & Francis
Abstract A UV-Spectrophotometric and Stability-indicating RP-HPLC methods are
developed and validated for the determination of Sofosbuvir (SOF) in tablet dosage form …
developed and validated for the determination of Sofosbuvir (SOF) in tablet dosage form …
Identification, isolation, structural characterization, in silico toxicity prediction and in vitro cytotoxicity assay of simeprevir acidic and oxidative degradation products
Simeprevir is a new direct-acting antiviral drug used for the treatment of chronic hepatitis C.
In this work, a simple, fast and economical chromatographic method was developed for the …
In this work, a simple, fast and economical chromatographic method was developed for the …