Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …

Background Postoperative cognitive dysfunction (POCD) is a common complication
following anesthesia and surgery. General anesthetic isoflurane has potential neurotoxicity …

Oxidative stress is a major risk factor that causes osteocyte cell death and bone loss. Prior
studies primarily focus on the function of cell surface expressed Cx43 channels. Here, we …

Osteoporosis (OP) is the most prevalent metabolic bone disease, characterized by the low
bone mass and microarchitectural deterioration of bone tissue. Glucocorticoid (GC) clinically …

Osteoporosis is a common disease in which the risk of fracture increases due to decreased
bone mass and qualitative skeletal changes. Selective androgen receptor modulators …

The extracellular milieu is a rich source of different stimuli and stressors. Some of them
depend on the chemical–physical features of the matrix, while others may come from the …

Neonatal encephalopathy (NE) is a pathological condition that describes a neurocognitive
malfunction in the newborn that arises from fetal, peripartum, or intrapartum events of …

Connexin 43 (Cx43) is the predominant connexin subtype expressed in osteocytes.
Osteocytes, accounting for 90%–95% of total bone cells, function as orchestrators …

In our body, all the cells are constantly sharing chemical and electrical information with other
cells. This intercellular communication allows them to respond in a concerted way to …