Cholesterol homeostasis is critical for normal growth and development. In addition to being
a major membrane lipid, cholesterol has multiple biological functions. These roles include …

Abstract 3β-Hydroxysterol Δ 24-reductase (DHCR24) catalyzes the conversion of
desmosterol to cholesterol. This ultimate step of cholesterol biosynthesis appears to be …

Accumulating evidences reveal that cellular cholesterol deficiency could trigger the onset of
Alzheimer's disease (AD). As a key regulator, 24-dehydrocholesterol reductase (DHCR24) …

Walnut oil is extracted from walnut kernels (Juglans regia Linne) or iron walnut kernels
(Juhlans sigillata Dode). The percentage of oil in walnuts is 52%–70%. The main …

Previous studies show that 3β-hydroxysterol-Δ24 reductase (DHCR24) has a remarked
decline in the brain of AD patients. In brain cholesterol synthetic metabolism, DHCR24 is …

Rationale: Lipid-free apolipoprotein (apo) AI and discoidal reconstituted high-density
lipoproteins (rHDL) containing apoA-I,(AI) rHDL, inhibit vascular inflammation by increasing …

The aims of this study were to identify the role and sites of action of serine proteinases (SPs)
in bone resorption, a process which involves a cascade of events, the central step of which …

Cholesterol plays a key role in many cellular processes, and is generated by cells through
de novo biosynthesis or acquired from exogenous sources through the uptake of low-density …

Abstract Aims microRNA-124 (miR-124) has recently been reported to be elevated in
cardiovascular disease. In this study, we aimed to investigate the exact role of miR-124 in …

Abstract Interleukin (IL)-22 regulates tissue inflammation and repair. Here we report
participation of the liver in IL-22-mediated cardiac repair after acute myocardial infarction …