Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy
L Wang, B Wang, C Wu, J Wang, M Sun - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …
Environmental enrichment and brain repair: harnessing the therapeutic effects of cognitive stimulation and physical activity to enhance experience‐dependent …
AJ Hannan - Neuropathology and applied neurobiology, 2014 - Wiley Online Library
Environmental enrichment (EE) increases levels of novelty and complexity, inducing
enhanced sensory, cognitive and motor stimulation. In wild‐type rodents, EE has been found …
enhanced sensory, cognitive and motor stimulation. In wild‐type rodents, EE has been found …
The interaction between autophagy and neuroinflammation in major depressive disorder: from pathophysiology to therapeutic implications
M Tang, T Liu, P Jiang, R Dang - Pharmacological research, 2021 - Elsevier
The past decade has revealed neuroinflammation as an important mechanism of major
depressive disorder (MDD). Nod-like receptors family pyrin domain containing 3 (NLRP3) …
depressive disorder (MDD). Nod-like receptors family pyrin domain containing 3 (NLRP3) …
Environmental enrichment improves cognitive deficits, AD hallmarks and epigenetic alterations presented in 5xFAD mouse model
C Griñán-Ferré, V Izquierdo, E Otero… - Frontiers in Cellular …, 2018 - frontiersin.org
Cumulative evidence shows that modifications in lifestyle factors constitute an effective
strategy to modulate molecular events related to neurodegenerative diseases, confirming …
strategy to modulate molecular events related to neurodegenerative diseases, confirming …
Differential impact of stress and environmental enrichment on corticolimbic circuits
Stress exposure can produce profound changes in physiology and behavior that can impair
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …
health and well-being. Of note, stress exposure is linked to anxiety disorders and depression …
Aggression in group-housed male mice: a systematic review
Simple Summary When male mice are kept in groups at animal facilities, aggressive
interactions between cage mates are not uncommon. Systematically reviewing previous …
interactions between cage mates are not uncommon. Systematically reviewing previous …
Inflammation and lithium: clues to mechanisms contributing to suicide-linked traits
Suicide is one of the leading causes of death in the United States, yet it remains difficult to
understand the mechanistic provocations and to intervene therapeutically. Stress is …
understand the mechanistic provocations and to intervene therapeutically. Stress is …
Environmental enrichment as an experience-dependent modulator of social plasticity and cognition
Social plasticity is the ability to adaptively change the expression of social behaviour
according to experience, allowing animals to optimize their social relationships in the …
according to experience, allowing animals to optimize their social relationships in the …
The effects of environmental enrichment on depressive and anxiety-relevant behaviors in socially isolated prairie voles
Objectives Social isolation is associated with depression, anxiety, and negative health
outcomes. Environmental enrichment, including environmental and cognitive stimulation …
outcomes. Environmental enrichment, including environmental and cognitive stimulation …
Effects of repeated social defeat on adolescent mice on cocaine‐induced CPP and self‐administration in adulthood: integrity of the blood–brain barrier
M Rodríguez‐Arias, S Montagud‐Romero… - Addiction …, 2017 - Wiley Online Library
Social stress in adulthood enhances cocaine self‐administration, an effect that has been
related with an increase in extracellular signal‐regulated kinase and p38α mitogen …
related with an increase in extracellular signal‐regulated kinase and p38α mitogen …