Nanofibrous insulin/vildagliptin core-shell PLGA scaffold promotes diabetic wound healing

CH Lee, DY Chen, MJ Hsieh, KC Hung… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Slow wound repair in diabetes is a serious adverse event that often results in
loss of a limb or disability. An advanced and encouraging vehicle is wanted to enhance …

Nanofibrous vildagliptin/PLGA membranes accelerate diabetic wound healing by angiogenesis

CH Lee, CH Huang, KC Hung, SC Huang, CC Kuo… - Pharmaceuticals, 2022 - mdpi.com
The inhibition of dipeptidyl peptidase-4 (DPP4) significantly enhances the wound closure
rate in diabetic patients with chronic foot ulcers. DPP4 inhibitors are only prescribed for …

Hybrid core–shell nanofibrous scaffolds/stents deliver angiotensin II receptor blocker to treat diabetic artery disease

CH Lee, MJ Hsieh, JG Roth, X Fu, CH Lu… - ACS Applied Polymer …, 2022 - ACS Publications
Most patients with diabetes suffer from impaired endothelial function and neointimal
thickening, which contribute to arterial atherosclerosis and increase the frequency of …

Enhanced diabetic wound healing using electrospun biocompatible PLGA-based saxagliptin fibrous membranes

CH Lee, SC Huang, KC Hung, CJ Cho, SJ Liu - Nanomaterials, 2022 - mdpi.com
Delayed diabetic wound healing is an adverse event that frequently leads to limb disability
or loss. A novel and promising vehicle for the treatment of diabetic wounds is required for …

Electrospun Materials for Biomedical Applications

HS Barud, FB De Sousa - Pharmaceutics, 2022 - mdpi.com
Considered a simple and versatile technique, electrospinning has emerged as a technology
for developing 3D materials for a wide range of applications. Electrospun fibers ranging from …

Bioinspired nanofibers: advancing drug delivery for enhanced therapeutic applications

AS Raikar, BB Bhat, SN Somnache - Journal of Applied …, 2024 - japsonline.com
Nanomedicine is advancing with bioinspired nanofiber-based drug delivery systems
(DDSs). This field explores the use of collagen and spider silk-like nanofibers to transport …

[PDF][PDF] Enhanced Diabetic Wound Healing Using Electrospun Biocompatible PLGA-Based Saxagliptin Fibrous Membranes. Nanomaterials 2022, 12, 3740

CH Lee, SC Huang, KC Hung, CJ Cho, SJ Liu - 2022 - pdfs.semanticscholar.org
Delayed diabetic wound healing is an adverse event that frequently leads to limb disability
or loss. A novel and promising vehicle for the treatment of diabetic wounds is required for …