[HTML][HTML] Role of m6A modification in regulating the PI3K/AKT signaling pathway in cancer
J Liu, X Gu, Z Guan, D Huang, H Xing… - Journal of Translational …, 2023 - Springer
Abstract The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway plays a crucial role in
the pathogenesis of cancer. The dysregulation of this pathway has been linked to the …
the pathogenesis of cancer. The dysregulation of this pathway has been linked to the …
Circulating tumor cell detection methods in renal cell carcinoma: A systematic review
Circulating tumor cells (CTCs) have a potential role as the missing renal cell carcinoma
(RCC) biomarker. However, the available evidence is limited, and detection methods lack …
(RCC) biomarker. However, the available evidence is limited, and detection methods lack …
[HTML][HTML] Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway
Y Liu, H Lv, X Li, J Liu, S Chen, Y Chen… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Of all pathological types of renal cell cancer (RCC), clear cell renal cell carcinoma (ccRCC)
has the highest incidence. Cyclovirobuxine (CVB), a triterpenoid alkaloid isolated from …
has the highest incidence. Cyclovirobuxine (CVB), a triterpenoid alkaloid isolated from …
Deciphering a Novel Necroptosis‐Related miRNA Signature for Predicting the Prognosis of Clear Cell Renal Carcinoma
J Bao, J Li, H Lin, W Zhang, B Guo, J Li… - Analytical Cellular …, 2022 - Wiley Online Library
Clear cell renal cell carcinoma (ccRCC) is the most common histological and devastating
subtype of renal cell carcinoma. Necroptosis is a form of programmed cell death that causes …
subtype of renal cell carcinoma. Necroptosis is a form of programmed cell death that causes …
[HTML][HTML] Tumor-educated platelets as a promising biomarker for blood-based detection of renal cell carcinoma
R Xiao, C Liu, B Zhang, L Ma - Frontiers in Oncology, 2022 - frontiersin.org
Purpose Tumor-educated platelets (TEPs) are a promising liquid biopsy in many cancers.
However, their role in renal cell carcinoma (RCC) is unknown. Thus, this study explored the …
However, their role in renal cell carcinoma (RCC) is unknown. Thus, this study explored the …
[HTML][HTML] Impact of inflammation and immunotherapy in renal cell carcinoma
J Shi, K Wang, Z Xiong, C Yuan, C Wang… - Oncology …, 2020 - spandidos-publications.com
Substantial research attention has been directed at exploring the mechanisms and treatment
of renal cell carcinoma (RCC). Indeed, the association between inflammation and tumor …
of renal cell carcinoma (RCC). Indeed, the association between inflammation and tumor …
[HTML][HTML] NUF2 drives clear cell renal cell carcinoma by activating HMGA2 transcription through KDM2A-mediated H3K36me2 demethylation
J Lin, X Chen, H Yu, S Min, Y Chen, Z Li… - International Journal of …, 2022 - ncbi.nlm.nih.gov
The poor sensitivity of clear cell renal cell carcinoma (ccRCC) to conventional chemotherapy
and radiotherapy makes its treatment challenging. The Ndc80 kinetochore complex …
and radiotherapy makes its treatment challenging. The Ndc80 kinetochore complex …
[HTML][HTML] UBE2T promotes proliferation and regulates PI3K/Akt signaling in renal cell carcinoma
P Hao, B Kang, Y Li, W Hao… - Molecular Medicine …, 2019 - spandidos-publications.com
Renal cell carcinoma (RCC) is a common malignant tumor globally. The overall survival of
patients with RCC is poor; one important factor is tumor heterogeneity. Ubiquitin‑conjugating …
patients with RCC is poor; one important factor is tumor heterogeneity. Ubiquitin‑conjugating …
[HTML][HTML] Oncogenic chromatin modifier KAT2A activates MCT1 to drive the glycolytic process and tumor progression in renal cell carcinoma
Y Guo, B Liu, Y Liu, W Sun, W Gao, S Mao… - Frontiers in cell and …, 2021 - frontiersin.org
Objectives This study aims to investigate the underlying mechanisms of KAT2A/MCT1 axis in
renal cell carcinoma (RCC), providing potential therapeutic targets. Methods We obtained …
renal cell carcinoma (RCC), providing potential therapeutic targets. Methods We obtained …
[HTML][HTML] A novel ZNF304/miR-183-5p/FOXO4 pathway regulates cell proliferation in clear cell renal carcinoma
LX Ren, BW Zeng, M Zhu, AN Zhao, B Shi… - Frontiers in …, 2021 - frontiersin.org
Zinc-finger protein 304 (ZNF304) plays a critical role in silencing genes through
transcription, regulating cell survival, proliferation, apoptosis, and differentiation during …
transcription, regulating cell survival, proliferation, apoptosis, and differentiation during …