Abstract The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway plays a crucial role in
the pathogenesis of cancer. The dysregulation of this pathway has been linked to the …

Circulating tumor cells (CTCs) have a potential role as the missing renal cell carcinoma
(RCC) biomarker. However, the available evidence is limited, and detection methods lack …

Of all pathological types of renal cell cancer (RCC), clear cell renal cell carcinoma (ccRCC)
has the highest incidence. Cyclovirobuxine (CVB), a triterpenoid alkaloid isolated from …

Clear cell renal cell carcinoma (ccRCC) is the most common histological and devastating
subtype of renal cell carcinoma. Necroptosis is a form of programmed cell death that causes …

Purpose Tumor-educated platelets (TEPs) are a promising liquid biopsy in many cancers.
However, their role in renal cell carcinoma (RCC) is unknown. Thus, this study explored the …

Substantial research attention has been directed at exploring the mechanisms and treatment
of renal cell carcinoma (RCC). Indeed, the association between inflammation and tumor …

The poor sensitivity of clear cell renal cell carcinoma (ccRCC) to conventional chemotherapy
and radiotherapy makes its treatment challenging. The Ndc80 kinetochore complex …

Renal cell carcinoma (RCC) is a common malignant tumor globally. The overall survival of
patients with RCC is poor; one important factor is tumor heterogeneity. Ubiquitin‑conjugating …

Objectives This study aims to investigate the underlying mechanisms of KAT2A/MCT1 axis in
renal cell carcinoma (RCC), providing potential therapeutic targets. Methods We obtained …

Zinc-finger protein 304 (ZNF304) plays a critical role in silencing genes through
transcription, regulating cell survival, proliferation, apoptosis, and differentiation during …