Large bone defects resulting from fractures and disease are a medical concern, being often
unable to heal spontaneously by the body's repair mechanisms. Bone tissue engineering …

Large bone defects are serious complications that are most commonly caused by extensive
trauma, tumour, infection, or congenital musculoskeletal disorders. If nonunion occurs …

Abstract Development of an optimal interface between bone and orthopaedic or dental
implants has taken place for many years. In order to determine whether a newly developed …

Bone implants and devices are a rapidly growing field within biomedical research, and
implants have the potential to significantly improve human and animal health. Animal …

Animal experimentation is carried out in consultation with the veterinary wing but it is
essential that be familiar with experimental protocols of animal model to be able to design …

A considerable number of international research groups as well as commercial entities work
on the development of new bone grafting materials, carriers, growth factors and specifically …

Critical-size bone defects, which require large-volume tissue reconstruction, remain a
clinical challenge. Bone engineering has the potential to provide new treatment concepts …

Given their native-like biological properties, high growth factor retention capacity and porous
nature, sulfated-polysaccharide-based scaffolds hold great promise for a number of tissue …

Increased use of implantable biomedical devices demonstrates their potential in treating a
wide variety of ailments and disorders in bone trauma and orthopaedic, reconstructive, and …

The scaffold chemical composition and pore architecture are critical for successful bone
regeneration. Although the effects of chemical composition, micron-scale pores, and …