Genetic susceptibility to lung cancer—light at the end of the tunnel?

AL Marshall, DC Christiani - Carcinogenesis, 2013 - academic.oup.com
Lung cancer is one of the most common and deadliest cancers in the world. The major socio-
environmental risk factor involved in the development of lung cancer is cigarette smoking …

Gene–environment interactions in heavy metal and pesticide carcinogenesis

S Tabrez, M Priyadarshini, S Priyamvada… - … /Genetic Toxicology and …, 2014 - Elsevier
Cancer is a complex disease involving a sequence of gene–environment interactions.
Lifestyle, genetics, dietary factors, and environmental pollutants can increase the risk of …

DNA methylation and smoking in Korean adults: epigenome-wide association study

MK Lee, Y Hong, SY Kim, SJ London, WJ Kim - Clinical epigenetics, 2016 - Springer
Background Exposure to cigarette smoking can increase the risk of cancers and
cardiovascular and pulmonary diseases. However, the underlying mechanisms of how …

Cyclin D1 Pro241Pro (CCND1-G870A) Polymorphism Is Associated with Increased Cancer Risk in Human Populations: A Meta-Analysis

N Pabalan, B Bapat, L Sung, H Jarjanazi… - … Biomarkers & Prevention, 2008 - AACR
The G870A polymorphism in the CCND1 gene may influence cancer risk. However, data
from published studies with individual low statistical power have been controversial. To …

Deep sequencing of plasma exosomal microRNA level in psoriasis vulgaris patients

XM Chen, DN Yao, MJ Wang, XD Wu, JW Deng… - Frontiers in …, 2022 - frontiersin.org
Psoriasis is a chronic skin disease affecting 1% to 3% of the world population. Psoriasis
vulgaris (PV) is the most common form of psoriasis. PV patients suffer from inflamed, pruritic …

Significant association of cyclin D1 promoter genotypes with asthma susceptibility in Taiwan

CH Li, KL Chiu, TC Hsia, TC Shen, LH Chen, CC Yu… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: The molecular mechanisms underlying the association between cell cycle
and asthma are poorly understood, and cyclin D1 (CCND1) is found to be upregulated in …

Association between Cyclin D1 G870A (rs9344) polymorphism and cancer risk in Indian population: meta-analysis and trial sequential analysis

N Thakur, S Kumari, R Mehrotra - Bioscience reports, 2018 - portlandpress.com
Introduction: Association between Cyclin D1 (CCND1) single nucleotide polymorphism
(SNP) rs9344 and cancer risk is paradoxical. Thus, we performed a meta-analysis to explore …

The significant association of CCND1 genotypes with colorectal cancer in Taiwan

CY Huang, CW Tsai, CM Hsu, WS Chang, HA Shui… - Tumor biology, 2015 - Springer
Colorectal cancer, one million cases of diagnosis worldwide annually, is one of the most
common malignant tumors and 20% incidence caused by low penetrance susceptibility …

Cyclin D1 G870A polymorphism and lung cancer risk: a meta-analysis

J Liu, Q Liao, Y Zhang, S Sun, C Zhong, X Liu - Tumor Biology, 2012 - Springer
Many studies have investigated the association between Cyclin D1 (CCND1) G870A
polymorphism and lung cancer risk, but the impact of CCND G870A polymorphism on lung …

Association of CCND1 rs9344 polymorphism with lung cancer susceptibility and clinical outcomes: a case-control study

C Mei, T Wang, B Xu, S Wu, X Zhang, Y Lv… - BMC Pulmonary …, 2024 - Springer
Abstract Background Cyclin D1 (CCND1) plays a pivotal role in cancer susceptibility and the
platinum-based chemotherapy response. This study aims to assess the relationship …