The failure to repair critical‐sized bone defects often leads to incomplete regeneration or
fracture non‐union. Tissue‐engineered grafts have been recognized as an alternative …

Therapeutic growth factor delivery typically requires supraphysiological dosages, which can
cause undesirable off-target effects. The aim of this study was to 3D bioprint implants …

Fracture healing is a complex, multistep process that is highly sensitive to mechanical
signaling. To optimize repair, surgeons prescribe immediate weight-bearing as-tolerated …

Interconnected porosity is critical to the design of regenerative scaffolds, as it permits cell
migration, vascularisation and diffusion of nutrients and regulatory molecules inside the …

With the progressive research of fabrication methodologies of biomaterials, hierarchically
porous structures and bioactive compositions have been identified to promote bone repair …

Background Osteonecrosis of the femoral head (ONFH) is a common disease.
Transplantation of bone marrow stem cells (BMSCs) is a promising method to treat ONFH …

Microbial diseases are a global health threat, leading to tremendous casualties and
economic losses. The strategy to treat microbial diseases falls into two broad categories …

The advent of precision manufacturing has enabled the creation of pores in metallic
scaffolds with feature size in the range of single microns. In orthopedic implants, pore …

Traumatic musculoskeletal injuries that result in bone defects or fractures often affect both
bone and the surrounding soft tissue. Clinically, these types of multi-tissue injuries have …

Tough porous cryogels with angiogenesis and osteogenesis features remain a design
challenge for utility in bone regeneration. Here, building off of the recent efforts to generate …