Allogeneic stem cell transplantation (allo-SCT) is a curable method for the treatment of
hematological malignancies. In the past two decades, the establishment of haploidentical …

Allogeneic hematopoietic cell transplantation (allo-HCT) is performed with curative intent for
high-risk blood cancers and bone marrow failure syndromes; yet the development of acute …

Chronic graft-versus-host disease (cGVHD) is characterized as autoimmune-like fibrosis and
antibody production mediated by pathogenic T cells and B cells. MicroRNA-17-92 (miR-17 …

Trichinella spiralis maintains chronic infections within its host, involving a variety of
immunomodulatory properties, the mechanisms of which have not been completely …

Transplantation of donor-derived allogeneic hematopoietic cells causes increased survival
in patients suffering from various blood cancers and other hematologic and immunologic …

Objective Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that are
abundant in humans, accounting for 1-10% of circulating T cells and about 2% of total T cells …

Dendritic cells (DCs) are professional antigen-presenting cells involved in the initiation of
immune responses. We generated a tolerogenic DC (tolDC) line that constitutively secretes …

Abstract Porcine circovirus (PCV) type 2 (PCV2), an immunosuppression pathogen, is often
found to increase the risk of other pathogenic infections. Yet the relative immune …

T-helper 1 and T-helper 17 lymphocytes mediate acute graft-versus-host disease (GvHD).
Interleukin 12 is critical for T-helper 1 differentiation and interleukin 23 for T-helper 17 …

Cell damage and death releases alarmins, self-derived immunomodulatory molecules that
recruit and activate the immune system. Unfortunately, numerous processes critical to the …