The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

Opioid use disorder (OUD) is influenced by genetic and environmental factors. While recent
research suggests epigenetic disturbances in OUD, this is mostly limited to DNA methylation …

The aim of this study is to explore the association between the aspartate amino transferase
(AST)/alanine aminotransferase (ALT) ratio and all-cause mortality (ACM) in stable coronary …

Little is known about whether DNA methylation (DNAm) of cytosine–phosphate–guanine
(CpG) sites at birth predicts patterns of lung function development. We used heel prick …

Background Maternal blood pressure levels reflect cardiovascular adaptation to pregnancy
and proper maternal-fetal exchanges through the placenta and are very sensitive to …

Childhood socioeconomic position (SEP) is associated with the development of adult
psychological outcomes, with DNA methylation (DNAm) as a mechanism to potentially …

Background and aims Epigenetic modifications are associated with hepatic fat accumulation
and non-alcoholic fatty liver disease (NAFLD). However, few epigenetic modifications …

Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are persistent organic
pollutants which may alter prenatal development, potentially through epigenetic …

Background: This study aimed to develop a prediction score named inflammatory score
based on proper integration of several inflammatory markers and investigate whether it was …

Quantifying cell proportions, especially for rare cell types in some scenarios, is of great value
in tracking signals associated with certain phenotypes or diseases. Although some methods …