IDH-wildtype lower-grade diffuse gliomas: the importance of histological grade and molecular assessment for prognostic stratification
G Berzero, AL Di Stefano, S Ronchi, F Bielle… - Neuro …, 2021 - academic.oup.com
Background Isocitrate dehydrogenase (IDH) wildtype (wt) grade II gliomas are a rare and
heterogeneous entity. Survival and prognostic factors are poorly defined. Methods We …
heterogeneous entity. Survival and prognostic factors are poorly defined. Methods We …
[HTML][HTML] Brain tumor classification using a combination of variational autoencoders and generative adversarial networks
Brain tumors are a pernicious cancer with one of the lowest five-year survival rates.
Neurologists often use magnetic resonance imaging (MRI) to diagnose the type of brain …
Neurologists often use magnetic resonance imaging (MRI) to diagnose the type of brain …
IDH wild-type lower-grade gliomas with glioblastoma molecular features: A systematic review and meta-analysis
S Nakasu, S Deguchi, Y Nakasu - Brain Tumor Pathology, 2023 - Springer
The WHO 2021 classification defines IDH wild type (IDHw) histologically lower-grade glioma
(hLGG) as molecular glioblastoma (mGBM) if TERT promoter mutation (pTERTm), EGFR …
(hLGG) as molecular glioblastoma (mGBM) if TERT promoter mutation (pTERTm), EGFR …
Characteristics and management of hydrocephalus in adult patients with cerebellar glioblastoma: lessons from a French nationwide series of 118 cases
The characteristics of hydrocephalus associated with cerebellar glioblastoma (cGB) remain
poorly known. The objectives were to describe the occurence of hydrocephalus in a French …
poorly known. The objectives were to describe the occurence of hydrocephalus in a French …
Gyriform infiltration as imaging biomarker for molecular glioblastomas
E Mesny, M Barritault, C Izquierdo, D Poncet… - Journal of Neuro …, 2022 - Springer
Background Molecular glioblastomas (ie without the histological but with the molecular
characteristics of IDH-wild-type glioblastoma) frequently lack contrast enhancement, which …
characteristics of IDH-wild-type glioblastoma) frequently lack contrast enhancement, which …
[HTML][HTML] PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma
S Tanaka, TT Batchelor, AJ Iafrate… - Acta Neuropathologica …, 2019 - Springer
Phosphatidylinositol 3-kinase signaling promotes cell growth and survival and is frequently
activated in infiltrative gliomas. Activating mutations in PIK3CA gene are observed in 6–15 …
activated in infiltrative gliomas. Activating mutations in PIK3CA gene are observed in 6–15 …
[HTML][HTML] Diffusion histogram profiles predict molecular features of grade 4 in histologically lower-grade adult diffuse gliomas following WHO classification 2021
R Kurokawa, A Hagiwara, M Kurokawa… - European …, 2024 - Springer
Abstract Objectives In the latest World Health Organization classification 2021, grade 4 adult
diffuse gliomas can be diagnosed with several molecular features even without histological …
diffuse gliomas can be diagnosed with several molecular features even without histological …
[HTML][HTML] Presurgical diagnosis of diffuse gliomas in adults: Post-WHO 2021 practical perspectives from radiologists in neuro-oncology units
A Pons-Escoda, C Majos, M Smits, L Oleaga - Radiología (English Edition), 2024 - Elsevier
Abstract The 2021 World Health Organization classification of CNS tumours was greeted
with enthusiasm as well as an initial potential overwhelm. However, with time and …
with enthusiasm as well as an initial potential overwhelm. However, with time and …
[HTML][HTML] Imaging features of localized IDH wild-type histologically diffuse astrocytomas: a single-institution case series
Y Kibe, K Motomura, F Ohka, K Aoki, H Shimizu… - Scientific Reports, 2023 - nature.com
Isocitrate dehydrogenase wild-type (IDH wt) diffuse astrocytomas feature highly infiltrative
patterns, such as a gliomatosis cerebri growth pattern with widespread involvement. Among …
patterns, such as a gliomatosis cerebri growth pattern with widespread involvement. Among …
Predicting TERT promoter mutation status using 1H-MR spectroscopy and stretched-exponential model of diffusion-weighted imaging in IDH-wildtype diffuse …
K Yamashita, R Hatae, K Kikuchi, D Kuga, N Hata… - Neuroradiology, 2023 - Springer
Purpose Isocitrate dehydrogenase (IDH)-wildtype diffuse astrocytic glioma with telomerase
reverse transcriptase (TERT) promoter mutation is defined as glioblastoma by the WHO …
reverse transcriptase (TERT) promoter mutation is defined as glioblastoma by the WHO …