Embryonic cells grow in environments that provide a plethora of physical cues, including
mechanical forces that shape the development of the entire embryo. Despite their …

Cells within developing tissues rely on morphogens to assess positional information.
Passive diffusion is the most parsimonious transport model for long-range morphogen …

Using four-dimensional whole-embryo light sheet imaging with improved and accessible
computational tools, we longitudinally reconstruct early murine cardiac development at …

Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …

Recent years have seen a dramatic increase in the application of organoids to
developmental biology, biomedical and translational studies. Organoids are large structures …

Gastrulation and neurulation are successive morphogenetic processes that play key roles in
shaping the basic embryonic body plan. Importantly, they operate through common cellular …

Synthetic embryology aims to develop embryo-like structures from stem cells to provide new
insight into early stages of mammalian development. Recent advances in synthetic …

The assembly of the embryo's primary axis is a fundamental landmark for the establishment
of the vertebrate body plan. Although the morphogenetic movements directing cell …

A striking property of vertebrate embryos is the emergence of a conserved body plan across
a wide range of organisms through the process of gastrulation. As the body plan unfolds …

The endoderm is the cell lineage which gives rise in the embryo to the organs of the
respiratory and gastrointestinal system. In the mouse this may be the germ layer with the …