MALDI-TOF-mass spectrometry (MS) has been successfully adapted for the routine
identification of microorganisms in clinical microbiology laboratories in the past 10 years …

Abstract The kinetoplastids Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
are causative agents of a diverse spectrum of human diseases: leishmaniasis, sleeping …

Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis (VL) and is
responsible for significant mortality and morbidity. Increasing resistance towards antimonial …

Background The present study aims to identify antigens in protein extracts of promastigote
and amastigote-like Leishmania (Leishmania) chagasi syn. L.(L.) infantum recognized by …

Amastin is a transmembrane glycoprotein found on the cell surfaces of trypanosomatid
parasites. Encoded by a large, diverse gene family, amastin was initially described from the …

Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …

Visceral leishmaniasis (VL) caused by Leishmania donovani is a major parasitic disease
prevalent in endemic regions of Bihar in India. In the absence of good chemotherapeutic …

Identification of novel antigens is essential for developing new diagnostic tests and
vaccines. We used DIGE to compare protein expression in amastigote and promastigote …

Leishmania spp., Trypanosoma cruzi, and Trypanosoma brucei are protozoan parasites that
cause a spectrum of fatal human diseases around the world. Recent completion of the …

Investigating the proteome of intracellular pathogens is often hampered by inadequate
methodologies to purify the pathogen free of host cell material. This has also precluded …