A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease

Q Zhang, JM Ames, RD Smith… - Journal of proteome …, 2009 - ACS Publications
The Maillard reaction, starting from the glycation of protein and progressing to the formation
of advanced glycation end-products (AGEs), is implicated in the development of …

Role of iron deficiency and overload in the pathogenesis of diabetes and diabetic complications

Q Liu, L Sun, Y Tan, G Wang, X Lin… - Current medicinal …, 2009 - ingentaconnect.com
Iron is one of the essential minerals that are required for a variety of molecules to maintain
their normal structures and functions and for cells to live, grow, and proliferate. The …

[HTML][HTML] Variation in the hemoglobin glycation index

JM Hempe, DS Hsia - Journal of Diabetes and its Complications, 2022 - Elsevier
A high hemoglobin glycation index (HGI) has been repeatedly associated with greater risk
for hypoglycemia in people with diabetes and greater risk for chronic vascular disease in …

Standardizing the haemoglobin glycation index

JM Hempe, S Yang, S Liu… - Endocrinology, Diabetes & …, 2021 - Wiley Online Library
Aims A high haemoglobin glycation index (HGI) is associated with greater risk for
hypoglycaemia and chronic vascular disease. Standardizing how the HGI is calculated …

Hypertension and diabetes mellitus as risk factors for asthma in Korean adults: the Sixth Korea National Health and Nutrition Examination Survey

KH Lee, HS Lee - International health, 2020 - academic.oup.com
Background Asthma is a chronic inflammatory disease that may associate with other chronic
diseases such as hypertension and diabetes. We observed the effects of blood pressure …

d-Galactose Decreases Anion Exchange Capability through Band 3 Protein in Human Erythrocytes

A Remigante, R Morabito, S Spinelli, V Trichilo… - Antioxidants, 2020 - mdpi.com
d-Galactose (d-Gal), when abnormally accumulated in the plasma, results in oxidative stress
production, and may alter the homeostasis of erythrocytes, which are particularly exposed to …

Increased plasma malondialdehyde and fructosamine in iron deficiency anemia: effect of treatment

RC Sundaram, N Selvaraj, G Vijayan, Z Bobby… - Biomedicine & …, 2007 - Elsevier
Glycation and lipid peroxidation are spontaneous reactions that are believed to play a key
role in the pathogenesis of many clinical disorders. Glycation of proteins is enhanced by …

Hemoglobin glycation index: a robust measure of hemoglobin A1c bias in pediatric type 1 diabetes patients

AA Soros, SA Chalew, RJ McCarter… - Pediatric …, 2010 - Wiley Online Library
Soros AA, Chalew SA, McCarter RJ, Shepard R, Hempe JM. Hemoglobin glycation index: a
robust measure of hemoglobin A1c bias in pediatric type 1 diabetes patients. Background …

Oxidative stress and protein glycation in primary hypothyroidism. Male/female difference

N Nanda, Z Bobby, A Hamide - Clinical and Experimental Medicine, 2008 - Springer
Oxidative stress (OS) has recently been documented in hypothyroidism, a disease more
prevalent in women. In general, OS is reported to be more prevalent in males. However, the …

Welch-weighted Egger regression reduces false positives due to correlated pleiotropy in Mendelian randomization

BC Brown, DA Knowles - The American Journal of Human Genetics, 2021 - cell.com
Modern population-scale biobanks contain simultaneous measurements of many
phenotypes, providing unprecedented opportunity to study the relationship between …