Abstract Tryptophan hydroxylase 2 (TPH2) is the rate-limiting enzyme in brain serotonin
synthesis. The TPH2 gene has frequently been investigated in relation to psychiatric …

BackgroundSuicide attempt (SA), which is one of the strongest predictors of completed
suicide, is common in major depressive disorder (MDD) but its prevalence across …

Suicide is a global public health problem that causes the loss of more than 800,000 lives
each year, principally among young people. In Brazil, the average mortality rate attributable …

Evidence supports the existence of an association between dyslipidemia, psychiatric
disorders, and suicide risk due to the effects of altered lipid profiles on serotoninergic neuron …

Objective To examine the associations between personality traits and suicidal ideation (SI)
and attempt (SA) in mood disorder patients and community controls. Method We recruited …

Background: Suicide behavior (SB) has been highly associated with the response to stress
and the hypothalamic–pituitary–adrenal (HPA) axis. The aim of this study was to summarize …

Background It remains unclear whether the dopaminergic and noradrenergic systems may
be implied in suicide attempt risk. In addition, although the serotonergic system has been …

Suicide is major public health concern; one million individuals worldwide die by suicide
each year of which there are many more attempts. Thus, it is imperative that robust and …

The addition of a methyl group to, typically, a cytosine‐guanine dinucleotide (CpG) creates
distinct DNA methylation patterns across the genome that can regulate gene expression …

Abstract Background Psychiatric comorbidity affects 24–65% patients with bipolar disorder
(BD), 45% of which have alcohol abuse/dependence (AAD). Despite the fact that BD has an …