Genomic and phenotypic heterogeneity in prostate cancer
From a clinical, morphological and molecular perspective, prostate cancer is a
heterogeneous disease. Primary prostate cancers are often multifocal, having …
heterogeneous disease. Primary prostate cancers are often multifocal, having …
The 2016 WHO classification of tumours of the urinary system and male genital organs—part B: prostate and bladder tumours
PA Humphrey, H Moch, AL Cubilla, TM Ulbright… - European urology, 2016 - Elsevier
It has been 12 yr since the publication of the last World Health Organization (WHO)
classification of tumours of the prostate and bladder. During this time, significant new …
classification of tumours of the prostate and bladder. During this time, significant new …
Histopathology of prostate cancer
PA Humphrey - Cold Spring Harbor perspectives …, 2017 - perspectivesinmedicine.cshlp.org
This review focuses on histopathological aspects of carcinoma of the prostate. A tissue
diagnosis of adenocarcinoma is often essential for establishing a diagnosis of prostate …
diagnosis of adenocarcinoma is often essential for establishing a diagnosis of prostate …
[HTML][HTML] DNA repair in prostate cancer: biology and clinical implications
Context For more precise, personalized care in prostate cancer (PC), a new classification
based on molecular features relevant for prognostication and treatment stratification is …
based on molecular features relevant for prognostication and treatment stratification is …
Prostate Cancer Biomarkers: From diagnosis to prognosis and precision-guided therapeutics
M Adamaki, V Zoumpourlis - Pharmacology & therapeutics, 2021 - Elsevier
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies and among the
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
leading causes of cancer-related death worldwide. It is a highly heterogeneous disease …
Cellular and molecular mechanisms underlying prostate cancer development: therapeutic implications
U Testa, G Castelli, E Pelosi - Medicines, 2019 - mdpi.com
Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …
Prostate cancer–specific mortality across Gleason scores in black vs nonblack men
Prostate Cancer–Specific Mortality Across Gleason Scores in Black vs Nonblack Men | Health
Disparities | JAMA | JAMA Network [Skip to Navigation] Our website uses cookies to enhance …
Disparities | JAMA | JAMA Network [Skip to Navigation] Our website uses cookies to enhance …
Exosomal and non‐exosomal urinary miRNAs in prostate cancer detection and prognosis
L Foj, F Ferrer, M Serra, A Arévalo, M Gavagnach… - The …, 2017 - Wiley Online Library
BACKGROUND MicroRNAs (miRNAs) are non‐coding small RNAs, involved in post‐
transcriptional regulation of many target genes. METHODS Five miRNAs that have been …
transcriptional regulation of many target genes. METHODS Five miRNAs that have been …
Aneuploidy drives lethal progression in prostate cancer
KH Stopsack, CA Whittaker, TA Gerke… - Proceedings of the …, 2019 - National Acad Sciences
Aneuploidy, defined as chromosome gains and losses, is a hallmark of cancer. However,
compared with other tumor types, extensive aneuploidy is relatively rare in prostate cancer …
compared with other tumor types, extensive aneuploidy is relatively rare in prostate cancer …
Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing
X Ma, J Guo, K Liu, L Chen, D Liu, S Dong, J Xia… - Molecular cancer, 2020 - Springer
Background The highly intra-tumoral heterogeneity and complex cell origination of prostate
cancer greatly limits the utility of traditional bulk RNA sequencing in finding better biomarker …
cancer greatly limits the utility of traditional bulk RNA sequencing in finding better biomarker …