The recently discovered functions of RNA dramatically expand the cellular roles for this
macromolecule. RNA can no longer be viewed as a passive element, working simply as an …

The ability of a drug or probe to cross a biological barrier has historically been viewed to be
a function of its intrinsic physical properties. This view has largely restricted drug design and …

Mounting evidence supports the presence of biologically relevant G‐quadruplexes in single‐
cell organisms, but the existence of endogenous G‐quadruplex structures in mammalian …

In the field of molecular recognition, the guanidinium group has been established as a
highly effective functional group in the binding of anionic guests. This moiety has been …

Remarkable findings have cemented the central dogma of biology, where the transfer of
genetic information from a sequence of nucleotides in DNA to a string of amino acids in …

G-quadruplex structures are among the most interesting and best-characterized DNA folding
motifs.[1] DNA sequences that can form stable G-quadruplexes in vitro have been implicated …

The emerging field of glycomics has been challenged by difficulties associated with studying
complex carbohydrates and glycoconjugates. Advances in the development of synthetic …

Molecular transporters have the ability to deliver drugs and probe molecules into cells and
tissues irrespective of their physical properties. We now report the design, synthesis, and …

Synthetic carbohydrates and glycoconjugates are used to study their roles in biological
important processes such as inflammation, cell–cell recognition, immunological response …

The surprising discovery that RNAs are the predominant gene products to emerge from the
human genome catalyzed a renaissance in RNA biology. It is now well-understood that …