Bioinspired exosome-like therapeutics and delivery nanoplatforms

M Lu, Y Huang - Biomaterials, 2020 - Elsevier
Exosomes have emerged as appealing candidate therapeutic agents and delivery
nanoplatforms due to their endogenous features and unique biological properties. However …

Lab-on-chip for exosomes and microvesicles detection and characterization

MS Chiriacò, M Bianco, A Nigro, E Primiceri, F Ferrara… - Sensors, 2018 - mdpi.com
Interest in extracellular vesicles and in particular microvesicles and exosomes, which are
constitutively produced by cells, is on the rise for their huge potential as biomarkers in a high …

Nanovesicles derived from iron oxide nanoparticles–incorporated mesenchymal stem cells for cardiac repair

JR Lee, BW Park, J Kim, YW Choo, HY Kim… - Science …, 2020 - science.org
Because of poor engraftment and safety concerns regarding mesenchymal stem cell (MSC)
therapy, MSC-derived exosomes have emerged as an alternative cell-free therapy for …

Mesenchymal stem cells reduce corneal fibrosis and inflammation via extracellular vesicle-mediated delivery of miRNA

G Shojaati, I Khandaker… - Stem cells …, 2019 - academic.oup.com
Mesenchymal stem cells from corneal stromal stem cells (CSSC) prevent fibrotic scarring
and stimulate regeneration of transparent stromal tissue after corneal wounding in mice …

Engineering a naturally-derived adhesive and conductive cardiopatch

BW Walker, RP Lara, CH Yu, ES Sani, W Kimball… - Biomaterials, 2019 - Elsevier
Myocardial infarction (MI) leads to a multi-phase reparative process at the site of damaged
heart that ultimately results in the formation of non-conductive fibrous scar tissue. Despite …

[HTML][HTML] Extracellular vesicles in cardiovascular theranostics

Y Bei, S Das, RS Rodosthenous, P Holvoet… - Theranostics, 2017 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are small bilayer lipid membrane vesicles that can be released
by most cell types and detected in most body fluids. EVs exert key functions for intercellular …

Stem cell-derived extracellular vesicles for cancer therapy and tissue engineering applications

CS Lee, M Lee, K Na, HS Hwang - Molecular Pharmaceutics, 2023 - ACS Publications
Recently, stem cells and their secretomes have attracted great attention in biomedical
applications, particularly extracellular vesicles (EVs). EVs are secretomes of cells for cell-to …

[HTML][HTML] Immunosuppressive effect of exosomes from mesenchymal stromal cells in defined medium on experimental colitis

ZJ Ma, YH Wang, ZG Li, Y Wang, BY Li… - … journal of stem …, 2019 - synapse.koreamed.org
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miR-381-abundant small extracellular vesicles derived from kartogenin-preconditioned mesenchymal stem cells promote chondrogenesis of MSCs by targeting …

H Jing, X Zhang, K Luo, Q Luo, M Yin, W Wang, Z Zhu… - Biomaterials, 2020 - Elsevier
Small extracellular vesicles (sEVs) derived from mesenchymal stem cells have been shown
to possess potent regenerative potential. In this study, we evaluated the chondrogenic effect …

Mesenchymal Stem Cell-Derived Long Noncoding RNAs in Cardiac Injury and Repair

T Tran, C Cruz, A Chan, S Awad, J Rajasingh, R Deth… - Cells, 2023 - mdpi.com
Cardiac injury, such as myocardial infarction and heart failure, remains a significant global
health burden. The limited regenerative capacity of the adult heart poses a challenge for …