Role of inflammatory molecules in the Alzheimer's disease progression and diagnosis

E Bagyinszky, V Van Giau, K Shim, K Suk… - Journal of the …, 2017 - Elsevier
Alzheimer's disease (AD) is a complex disorder and the most common form of
neurodegenerative dementia. Several genetic, environmental, and physiological factors …

Role of redox signaling in neuroinflammation and neurodegenerative diseases

HL Hsieh, CM Yang - BioMed research international, 2013 - Wiley Online Library
Reactive oxygen species (ROS), a redox signal, are produced by various enzymatic
reactions and chemical processes, which are essential for many physiological functions and …

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

SG Snowden, AA Ebshiana, A Hye, Y An… - PLoS …, 2017 - journals.plos.org
Background The metabolic basis of Alzheimer disease (AD) pathology and expression of AD
symptoms is poorly understood. Omega-3 and-6 fatty acids have previously been linked to …

Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics

E Trushina, T Dutta, XMT Persson, MM Mielke… - PloS one, 2013 - journals.plos.org
Alzheimer's Disease (AD) currently affects more than 5 million Americans, with numbers
expected to grow dramatically as the population ages. The pathophysiological changes in …

The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina

JP SanGiovanni, EY Chew - Progress in retinal and eye research, 2005 - Elsevier
In this work we advance the hypothesis that omega-3 (ω-3) long-chain polyunsaturated fatty
acids (LCPUFAs) exhibit cytoprotective and cytotherapeutic actions contributing to a number …

Lead (Pb) exposure enhances expression of factors associated with inflammation

E Metryka, K Chibowska, I Gutowska… - International journal of …, 2018 - mdpi.com
The human immune system is constantly exposed to xenobiotics and pathogens from the
environment. Although the mechanisms underlying their influence have already been at …

Effects of rosmarinic acid on nervous system disorders: an updated review

M Ghasemzadeh Rahbardar… - … Archives of Pharmacology, 2020 - Springer
Nowadays, the worldwide interest is growing to use medicinal plants and their active
constituents to develop new potent medicines with fewer side effects. Precise dietary …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration

L Calderon-Garciduenas, RR Maronpot… - Toxicologic …, 2003 - journals.sagepub.com
Acute, subchronic, or chronic exposures to particulate matter (PM) and pollutant gases affect
people in urban areas and those exposed to fires, disasters, and wars. Respiratory tract …

Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders

JW Phillis, LA Horrocks, AA Farooqui - Brain research reviews, 2006 - Elsevier
Three enzyme systems, cyclooxygenases that generate prostaglandins, lipoxygenases that
form hydroxy derivatives and leukotrienes, and epoxygenases that give rise to …