Introduction The aim of this study was to investigate the role of the proinflammatory axis TNF-
α–TNFR1 in experimentally induced periapical inflammation and bone resorption in mice …

Introduction MicroRNAs have been shown to play a role in the pathogenesis of apical
periodontitis. Upregulation of miR-10a-5p and downregulation of miR-891a-5p were …

Apical periodontitis is a common clinical disease caused by bacteria; bacterial metabolites
can cause an imbalance in bone homeostasis, bone mass reduction, and tooth loss. Bone …

Apical periodontitis (AP) is an infectious disease that causes periapical tissue inflammation
and bone destruction. Ferroptosis, a novel type of regulated cell death, is closely associated …

Dental caries is a common infectious disease worldwide. Current conventional therapies
lack specific antimicrobial effects against Streptococcus mutans, a key bacterium that …

Older age is associated with reduced immune function. Our aim was to study how age
affects the development of apical periodontitis (AP). AP was induced in two age groups of …

Abstract Introduction Matrix metalloproteinases (MMPs) and tissue inhibitors of matrix
metalloproteinases (TIMPs) are considered important mediators of the periapical immune …

Introduction Chronic apical periodontitis (CAP) is a common infectious disease of the oral
cavity. Immune responses and osteoclastogenesis of monocytes/macrophages play a …

Objective The aim of this study was to demonstrate the influence of the virulence factor
GroEL on osteoblast behavior by characterizing the changes of secreted gelatinases …

Introduction: There is a morphological assessment of the damaged area and the
inflammatory response of periodontal tissues after therapy. It seems relevant to evaluate the …