Asymmetric sigmatropic rearrangement is a powerful organic transformation via substrate-
reorganization to efficiently increase molecular complexity from readily accessible starting …

Among the available methods to increase the molecular complexity, sigmatropic
rearrangements occupy a distinct position in organic synthesis. Despite being known for …

Rearrangement reactions occupy a special place within the canon of organic synthesis, by
virtue of the inherently high efficiency of chemical processes which form and break bonds by …

A tandem relay catalytic protocol using both Pd and isothiourea catalysis has been
developed for the enantioselective synthesis of α-amino acid derivatives containing two …

Benzotetramisole promotes the catalytic asymmetric [2, 3]-rearrangement of allylic
quaternary ammonium salts (either isolated or prepared in situ from p-nitrophenyl …

With modern methods for asymmetric catalysis breaking ground, the use of chiral auxiliaries
seems to be old-fashioned and rather inefficient. However, for many transformations, chiral …

A mechanistic study of the isothiourea-catalyzed enantioselective [2, 3]-rearrangement of
allylic ammonium ylides is described. Reaction kinetic analyses using 19F NMR and density …

A highly practical and efficient asymmetric synthesis of chiral homoallylic amines by In-
mediated allylation of chiral N-tert-butanesulfinyl imines in aqueous media at room …

Ammonium ylide based [2, 3]-sigmatropic and [1, 2]-Stevens rearrangements enable the
transformation of tertiary amines into rearranged and functionalized intermediates en route …

A systematic study was performed to establish general synthesis protocols for forming
enantiomerically pure macrocyclic dipeptide lactams. Focusing on macrocycles of 8-, 9-, and …