[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

[HTML][HTML] Recent advances in antiviral drug development towards dengue virus

B Troost, JM Smit - Current opinion in virology, 2020 - Elsevier
Highlights•Evaluating drug efficacy, specificity and toxicity may help to develop an optimal
treatment regime for in vivo studies.•Measuring time to resolve viremia in vivo may help to …

Molecular mechanisms of antiviral agents against dengue virus

MF Lee, YS Wu, CL Poh - Viruses, 2023 - mdpi.com
Dengue is a major global health threat causing 390 million dengue infections and 25,000
deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of …

Updates on dengue vaccine and antiviral: where are we heading?

H Norshidah, R Vignesh, NS Lai - Molecules, 2021 - mdpi.com
Approximately 100–400 million people from more than 100 countries in the tropical and
subtropical world are affected by dengue infections. Recent scientific breakthroughs have …

The medicinal chemistry of dengue virus

MAM Behnam, C Nitsche, V Boldescu… - Journal of medicinal …, 2016 - ACS Publications
The dengue virus and related flaviviruses are an increasing global health threat. In this
perspective, we comment on and review medicinal chemistry efforts aimed at the prevention …

Anti-dengue infectivity evaluation of bioflavonoid from Azadirachta indica by dengue virus serine protease inhibition

VD Dwivedi, S Bharadwaj, S Afroz, N Khan… - Journal of …, 2021 - Taylor & Francis
Dengue virus (DENV) serine protease enzyme, ie NS2B-NS3pro (non-structural protein 2B-
non-structural protein 3) has been approved as prime drug target for the drug discovery …

Antimicrobial peptides and their potential application in antiviral coating agents

ED Freitas, RA Bataglioli, J Oshodi… - Colloids and Surfaces B …, 2022 - Elsevier
Coronavirus pandemic has evidenced the importance of creating bioactive materials to
mitigate viral infections, especially in healthcare settings and public places. Advances in …

[HTML][HTML] Peptides as therapeutic agents for dengue virus

MF Chew, KS Poh, CL Poh - International journal of medical …, 2017 - ncbi.nlm.nih.gov
Dengue is an important global threat caused by dengue virus (DENV) that records an
estimated 390 million infections annually. Despite the availability of CYD-TDV as a …

Dengue virus: pathogenesis and potential for small molecule inhibitors

N Chauhan, KK Gaur, TR Asuru… - Bioscience reports, 2024 - portlandpress.com
Dengue, caused by dengue virus (DENV), is now endemic in nearly 100 countries and
infection incidence is reported in another 30 countries. Yearly an estimated 400 million …

Dengue virus and its inhibitors: a brief review

YS Tian, Y Zhou, T Takagi, M Kameoka… - Chemical and …, 2018 - jstage.jst.go.jp
The global occurrence of viral infectious diseases poses a significant threat to human health.
Dengue virus (DENV) infection is one of the most noteworthy of these infections. According …