[HTML][HTML] Potassium channels, glucose metabolism and glycosylation in cancer cells
A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2023 - mdpi.com
Potassium channels emerge as one of the crucial groups of proteins that shape the biology
of cancer cells. Their involvement in processes like cell growth, migration, or electric …
of cancer cells. Their involvement in processes like cell growth, migration, or electric …
Drug repurposing strategies for non-cancer to cancer therapeutics
S Singhal, P Maheshwari… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Global efforts invested in the prevention and treatment of cancer need to be repositioned to
develop safe, effective, and economic anticancer therapeutics by adopting rational …
develop safe, effective, and economic anticancer therapeutics by adopting rational …
Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia
Dopamine (DA) D2-like receptors in both the central nervous system (CNS) and the
periphery are key modulators of metabolism. Moreover, disruption of D2-like receptor …
periphery are key modulators of metabolism. Moreover, disruption of D2-like receptor …
Drug Repurposing in Cancer
NR Shruthi, M Samatha Jain, H Ganesan… - Drug Repurposing for …, 2023 - Springer
The discovery of drug compounds has a long history in drug repurposing, notably by
fortuitous findings. It has taken a new path in the creation of novel therapeutics based on …
fortuitous findings. It has taken a new path in the creation of novel therapeutics based on …
MD simulation-based screening approach identified tolvaptan as a potential inhibitor of Eg5
J Sebastian, D Raghav, K Rathinasamy - Molecular Diversity, 2023 - Springer
We discovered tolvaptan as a new Eg5 inhibitor using molecular dynamics simulation-based
virtual screening. The Eg5-monastrol, Eg5-ispinesib, and Eg5-STLC complexes with …
virtual screening. The Eg5-monastrol, Eg5-ispinesib, and Eg5-STLC complexes with …
[PDF][PDF] In Vitro and In Silico studies of Neophytadiene; A Diterpene Isolated from Aeschynomene Elaphroxylon (Guill. &Perr.) Taub. as Apoptotic
Abstract Aeschynomene elaphroxylon (Guill. & Perr.) Taub. is a large aquatic shrub native to
Madagascar and tropical Africa and cultivated in Egypt. Petroleum ether extract showed …
Madagascar and tropical Africa and cultivated in Egypt. Petroleum ether extract showed …
Repurposing Mitragynine as Anti-SARS-CoV-2 Agent Evidenced by In Silico Predictive Approach
The ongoing coronavirus disease-2019 (COVID-19) catastrophe calls for the development of
therapeutic approaches to combat the disease. Therefore, an in silico study was conducted …
therapeutic approaches to combat the disease. Therefore, an in silico study was conducted …
In Vitroand in Silico studies of Neophytadiene; A Diterpene Isolated Fromaeschynomene Elaphroxylon (Guill. &Perr.) Taub. as Apoptotic Inducer
AH Selmy, MM Hegazy, AA El-Hela… - Egyptian Journal of …, 2023 - journals.ekb.eg
Aeschynomene elaphroxylon (Guill. & Perr.) Taub. is a large aquatic shrub native to
Madagascar and tropical Africa and cultivated in Egypt. Petroleum ether extract showed …
Madagascar and tropical Africa and cultivated in Egypt. Petroleum ether extract showed …
Design and synthesis of n-containing bicyclic scaffolds for library generation
ÓM Conway - 2022 - etheses.bham.ac.uk
In recent years, the field of drug discovery has begun to move away from targets which have
traditionally been deemed “druggable” and has placed a focus on the exploration of novel …
traditionally been deemed “druggable” and has placed a focus on the exploration of novel …