Extracellular vesicles: new classification and tumor immunosuppression
Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
Tissue-derived extracellular vesicles in cancer progression: mechanisms, roles, and potential applications
Z Ye, W Chen, G Li, J Huang, J Lei - Cancer and Metastasis Reviews, 2024 - Springer
Extracellular vesicles (EVs) are small lipid bilayer–enclosed vesicles that mediate vital
cellular communication by transferring cargo between cells. Among these, tissue-derived …
cellular communication by transferring cargo between cells. Among these, tissue-derived …
[HTML][HTML] EpEX, the soluble extracellular domain of EpCAM, resists cetuximab treatment of EGFR-high head and neck squamous cell carcinoma
K Umemori, K Ono, T Eguchi, H Kawai, T Nakamura… - Oral Oncology, 2023 - Elsevier
Abstract Objectives Cetuximab (Cmab) is a molecularly targeted monoclonal antibody drug
for head and neck squamous cell carcinoma (HNSC), although cetuximab resistance is a …
for head and neck squamous cell carcinoma (HNSC), although cetuximab resistance is a …
Comprehensive method for exosome isolation and proteome analysis for detection of CCN factors in/on exosomes
T Eguchi, Y Okusha, Y Lu, K Ono, EA Taha… - CCN Proteins: Methods …, 2022 - Springer
Abstract Cellular Communication Network (CCN) proteins are secretory growth factors often
associated with extracellular matrix (ECM) and extracellular vesicles (EVs) such as …
associated with extracellular matrix (ECM) and extracellular vesicles (EVs) such as …
Positive regulation of S-adenosylmethionine on chondrocytic differentiation via stimulation of polyamine production and the gene expression of chondrogenic …
LD Hoang, E Aoyama, M Hiasa, H Omote… - International journal of …, 2023 - mdpi.com
S-adenosylmethionine (SAM) is considered to be a useful therapeutic agent for
degenerative cartilage diseases, although its mechanism is not clear. We previously found …
degenerative cartilage diseases, although its mechanism is not clear. We previously found …
Novel mechanism of cisplatin resistance in head and neck squamous cell carcinoma involving extracellular vesicles and a copper transporter system
T Ogawa, K Ono, S Ryumon, H Kawai… - Head & …, 2024 - Wiley Online Library
Background Cisplatin (CDDP) plays a central role in chemotherapy for head and neck
squamous cell carcinoma (HNSCC), but drug resistance in HNSCC chemotherapy remains …
squamous cell carcinoma (HNSCC), but drug resistance in HNSCC chemotherapy remains …
Transfection, spinfection, exofection, and luciferase assays for analysis of CCN genes expression mechanism
T Eguchi, Y Lu, EA Taha, Y Okusha - CCN Proteins: Methods and …, 2022 - Springer
Cell communication network factor 2 (CCN2), also known as connective tissue growth factor
(CTGF), is protein inducible in response to TGFβ/Smad signal or the transcriptional activity of …
(CTGF), is protein inducible in response to TGFβ/Smad signal or the transcriptional activity of …
Protocol for CRISPR/Cas genome editing for investigating cell communication network
Y Okusha, T Eguchi - CCN Proteins: Methods and Protocols, 2022 - Springer
Abstract The Cellular Communication Network Factor (CCN) family is composed of six
members: CCN1/CYR61, CCN2/CTGF, CCN3/NOV, CCN4/WISP1, CCN5/WISP2, and …
members: CCN1/CYR61, CCN2/CTGF, CCN3/NOV, CCN4/WISP1, CCN5/WISP2, and …