Brucella can parasitize within human antigen-presenting cells modifying phagocytosis,
phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis. Subversion …

Brucellosis, caused by the intracellular pathogens Brucella, is one of the major zoonotic
infections. Considering the economic burden, its prevalence has been a health concern …

Objective Owing to involvement of host genetic factors in susceptibility to brucellosis
infection and its outcome, this study aimed to carry out a comprehensive systematic review …

Brucella spp. are gram-negative, facultative and intracellular bacteria that can cause chronic
zoonotic infections in humans (Young, 2005). The organism can be transmitted from animals …

Several genes encoding for different cytokines may play crucial roles in host susceptibility to
Brucellosis, since the cytokine production capacity varies among individuals and depends …

Activation of macrophages and their antimicrobial activities by interferon-gamma (IFN-γ)
plays a crucial role in controlling Brucella infection. Interleukin-4 (IL-4) antagonizes the …

Background: It seems that polymorphism in the regulatory areas of cytokine genes affects
the cytokine production capacity and may play a role in the development of infectious …

Background Brucellosis is a quite normal zoonotic infection, which is caused by immediate
contact with animals infected with Brucella or its products. IL-10 (− 1082 G/A,− 819 C/T …

Although inflammation is emerging as a candidate prostate cancer risk factor, the T-helper
cytokine-rich [interleukins (IL)-5, 13 and 4] chromosomal region at 5q31. 1 has been …

Natural resistance against brucellosis was reviewed from historical and biological
perspectives with regard to animals, humans and Brucella spp. Unfortunately, brucellosis …