Regulation of Biofilm Exopolysaccharide Biosynthesis and Degradation in Pseudomonas aeruginosa

LZ Ma, D Wang, Y Liu, Z Zhang… - Annual review of …, 2022 - annualreviews.org
Microbial communities enmeshed in a matrix of macromolecules, termed as biofilms, are the
natural setting of bacteria. Exopolysaccharide is a critical matrix component of biofilms …

Regulation of bacterial virulence by Csr (Rsm) systems

CA Vakulskas, AH Potts, P Babitzke… - Microbiology and …, 2015 - Am Soc Microbiol
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …

Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation

JPJ Hall, RCT Wright, E Harrison, KJ Muddiman… - PLoS …, 2021 - journals.plos.org
Plasmids play an important role in bacterial genome evolution by transferring genes
between lineages. Fitness costs associated with plasmid carriage are expected to be a …

Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles

SL Chua, Y Liu, JKH Yam, Y Chen, RM Vejborg… - Nature …, 2014 - nature.com
Bacteria assume distinct lifestyles during the planktonic and biofilm modes of growth.
Increased levels of the intracellular messenger c-di-GMP determine the transition from …

Global role of the bacterial post-transcriptional regulator CsrA revealed by integrated transcriptomics

AH Potts, CA Vakulskas, A Pannuri, H Yakhnin… - Nature …, 2017 - nature.com
CsrA is a post-transcriptional regulatory protein that is widely distributed among bacteria.
This protein influences bacterial lifestyle decisions by binding to the 5′ untranslated and/or …

The type VI secretion system: a dynamic system for bacterial communication?

M Gallique, M Bouteiller, A Merieau - Frontiers in microbiology, 2017 - frontiersin.org
Numerous studies in Gram-negative bacteria have focused on the T ype VI S ecretion S
ystems (T6SSs), Q uorum S ensing (QS), and social behavior, such as in biofilms. These …

Small RNAs, 5′ UTR elements and RNA-binding proteins in intracellular bacteria: impact on metabolism and virulence

G Oliva, T Sahr, C Buchrieser - FEMS microbiology reviews, 2015 - academic.oup.com
Sequencing-based studies have illuminated increased transcriptional complexity within the
genome structure of bacteria and have resulted in the identification of many small regulatory …

Plasmids manipulate bacterial behaviour through translational regulatory crosstalk

CMA Thompson, JPJ Hall, G Chandra, C Martins… - PLoS …, 2023 - journals.plos.org
Beyond their role in horizontal gene transfer, conjugative plasmids commonly encode
homologues of bacterial regulators. Known plasmid regulator homologues have highly …

Transcriptomic-proteomic integration: A powerful synergy to elucidate the mechanisms of meat spoilage in the cold chain

AP Bassey, K Ye, C Li, G Zhou - Trends in Food Science & Technology, 2021 - Elsevier
Background The ubiquity and diversity of spoilage microorganisms in the cold chain have
caused incessant spoilage occurrences, resulting in significant economic losses to food …

RsmW, Pseudomonas aeruginosa small non-coding RsmA-binding RNA upregulated in biofilm versus planktonic growth conditions

CL Miller, M Romero, SLR Karna, T Chen, S Heeb… - BMC microbiology, 2016 - Springer
Background Biofilm development, specifically the fundamentally adaptive switch from acute
to chronic infection phenotypes, requires global regulators and small non-coding regulatory …