Since the discovery of aquaporins, it has become clear that the various mammalian
aquaporins play critical physiological roles in water and ion balance in multiple tissues …

With the emergence of novel technologies and ground breaking concepts in BBB basic
research in the past decades, the researchers' attention on the critical role of blood brain …

Neurologic conditions including stroke, Alzheimer disease, Parkinson disease, and
Huntington disease are leading causes of death and long-term disability in the United …

A divergence in the supply and consumption of oxygen in brain tissue initiates complex
cycle of biochemical and molecular events resulting in neuronal death. To overcome such …

The neuroinflammatory response to traumatic brain injury (TBI) is critical to both
neurotoxicity and neuroprotection, and has been proposed as a potentially modifiable driver …

Hypoxia, depending upon its magnitude and circumstances, evokes a spectrum of mild to
severe acid–base changes ranging from alkalosis to acidosis, which can alter many …

The present study, using a rodent model of closed-head diffuse traumatic brain injury (TBI),
investigated the role of dysregulated aquaporins (AQP) 4 and 9, as well as hypoxia …

Cerebrovascular disease (CVD) ranks as the top three health risks, specially cerebral
ischemia characterized with the damage of blood–brain barrier (BBB). The angiotensin Ang …

Background and Purpose—Ethanol consumption is inversely associated with the risk of
ischemic stroke, suggesting a neuroprotective effect. In a rat model of transient cerebral …

Heat acclimation (HA), a well-established preconditioning model, confers neuroprotection in
rodent models of traumatic brain injury (TBI). It increases neuroprotective factors, among …