[HTML][HTML] A literature review of real-world effectiveness and safety of dupilumab for atopic dermatitis

M Kamata, Y Tada - JID Innovations, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic inflammatory skin disease with pruritus, characterized by
recurrent eczema with exacerbations and remissions. AD impairs patients' QOL and places …

Dupilumab ocular side effects in patients with atopic dermatitis: a systematic review

N Neagu, C Dianzani, G Avallone… - Journal of the …, 2022 - Wiley Online Library
Atopic dermatitis (AD) is a chronic, inflammatory skin disorder that most frequently occurs in
children, but it can also affect adults. Even though most AD cases can be managed with …

Conjunctivitis in adult patients with moderate‐to‐severe atopic dermatitis: results from five tralokinumab clinical trials

A Wollenberg, LA Beck… - British Journal of …, 2022 - academic.oup.com
Background Tralokinumab, a fully human IgG4 monoclonal antibody that specifically binds
with high affinity to interleukin‐13, effectively reduces moderate‐to‐severe atopic dermatitis …

Lebrikizumab for the treatment of moderate-to-severe atopic dermatitis

D Bernardo, T Bieber, T Torres - American Journal of Clinical Dermatology, 2023 - Springer
Atopic dermatitis (AD) is a common, heterogeneous, inflammatory skin disorder
characterized by chronic or relapsing eczematous lesions with intense pruritus and …

[HTML][HTML] Targeting interleukin 13 for the treatment of atopic dermatitis

Y Lytvyn, M Gooderham - Pharmaceutics, 2023 - mdpi.com
Atopic dermatitis (AD) is a common chronic inflammatory skin condition that has a significant
impact on a patient's quality of life and requires ongoing management. Conventional topical …

[HTML][HTML] Selective IL-13 inhibitors for the treatment of atopic dermatitis

F Gonçalves, E Freitas, T Torres - Drugs in context, 2021 - ncbi.nlm.nih.gov
Background Atopic dermatitis (AD) is one of the most common chronic inflammatory skin
diseases worldwide. AD pathogenesis is multifactorial, involving environmental and genetic …

Effects of renal impairment on the pharmacokinetics of abrocitinib and its metabolites

EQ Wang, V Le, JA Winton, S Tripathy… - The Journal of …, 2022 - Wiley Online Library
Abrocitinib, an oral once‐daily Janus kinase 1 selective inhibitor, is under development for
the treatment of atopic dermatitis. This phase 1, nonrandomized, open‐label, single‐dose …

Ocular surface disorders associated with the use of dupilumab based on WHO VigiBase

S Park, JH Lee, JH Park, SH Park, SY Park, YW Jung… - Scientific reports, 2021 - nature.com
Dupilumab is a dual inhibitor of interleukin-4 and interleukin-13 and is mainly used to treat
moderate-to-severe atopic dermatitis. Post-marketing safety data related to dupilumab have …

Inhibition of IL-13: a new pathway for atopic dermatitis

K Ratnarajah, M Le, A Muntyanu… - Journal of …, 2021 - journals.sagepub.com
Dupilumab, a monoclonal antibody against the common receptor of interleukin (IL)-4 and IL-
13, was the first biologic therapy approved in Canada for treatment of moderate-to-severe …

Ocular adverse events in patients with atopic dermatitis treated with upadacitinib: a real-life experience

F Gelato, L Mastorino, P Quaglino, G Cavaliere… - Dermatitis®, 2023 - liebertpub.com
Background: Dupilumab, an interleukin (IL)-4 receptor-α inhibitor that blocks IL-4 and IL-13
signaling pathways, is an effective and well-tolerated therapy for moderate-to-severe atopic …